医学检验与临床
醫學檢驗與臨床
의학검험여림상
MEDICAL LATORATORY SCIENCE AND CLINICES
2015年
2期
20-21,76
,共3页
25-羟基维生素D%心血管疾病%诊断
25-羥基維生素D%心血管疾病%診斷
25-간기유생소D%심혈관질병%진단
25 (OH) D%Cardiovascular disease%Diagnosis
目的：探讨维生素D定量在心血管疾病诊断中的作用。方法：随机选取我院2009年3月至2013年4月收入的心血管疾病患者110例为研究对象，作为观察组，另取110例健康人为对照组，分别对两组血清25-羟基维生素D [25(OH) D]进行定量检测。结果：观察组患者血清25(OH)D的浓度≥30ng/ml的仅有7例，而对照组有101例，两组相比差异显著[χ2=160.05；P<0.01]；观察组中急性心肌梗死、不稳定性心绞痛、稳定性心绞痛、其他冠心病、心衰患者的血清25(OH) D定量结果比较无明显差异，无统计学意义（P>0.05）；与对照组比较均明显较低，有统计学意义[t=19.75；P<0.05]。结论：血清维生素D的浓度与心血管疾病的发生、发展呈负相关，临床可通过定量检测血清维生素D对心血管疾病进行辅助诊断。
目的：探討維生素D定量在心血管疾病診斷中的作用。方法：隨機選取我院2009年3月至2013年4月收入的心血管疾病患者110例為研究對象，作為觀察組，另取110例健康人為對照組，分彆對兩組血清25-羥基維生素D [25(OH) D]進行定量檢測。結果：觀察組患者血清25(OH)D的濃度≥30ng/ml的僅有7例，而對照組有101例，兩組相比差異顯著[χ2=160.05；P<0.01]；觀察組中急性心肌梗死、不穩定性心絞痛、穩定性心絞痛、其他冠心病、心衰患者的血清25(OH) D定量結果比較無明顯差異，無統計學意義（P>0.05）；與對照組比較均明顯較低，有統計學意義[t=19.75；P<0.05]。結論：血清維生素D的濃度與心血管疾病的髮生、髮展呈負相關，臨床可通過定量檢測血清維生素D對心血管疾病進行輔助診斷。
목적：탐토유생소D정량재심혈관질병진단중적작용。방법：수궤선취아원2009년3월지2013년4월수입적심혈관질병환자110례위연구대상，작위관찰조，령취110례건강인위대조조，분별대량조혈청25-간기유생소D [25(OH) D]진행정량검측。결과：관찰조환자혈청25(OH)D적농도≥30ng/ml적부유7례，이대조조유101례，량조상비차이현저[χ2=160.05；P<0.01]；관찰조중급성심기경사、불은정성심교통、은정성심교통、기타관심병、심쇠환자적혈청25(OH) D정량결과비교무명현차이，무통계학의의（P>0.05）；여대조조비교균명현교저，유통계학의의[t=19.75；P<0.05]。결론：혈청유생소D적농도여심혈관질병적발생、발전정부상관，림상가통과정량검측혈청유생소D대심혈관질병진행보조진단。
Objective:To explore the role of Vitamin D in the diagnosis of cardiovascular disease. Methods:We randomly chose 110 patients as the observation group from those who received their treatment for cardiovascular disease in our hospital from March, 2009 to April, 2013, and we chose 110 healthy people as the control group. Then we detected quantitatively 25 (OH) D in each group.Results:In the observation group, only 7 cases 25 (OH) D are with over 30ng/ml while, 101 cases are with that level in the control group . There exists a great disparity between them (χ2=160.05;P<0.01). In the observation group, the quantitative valueof 25 (OH) D of patients with the acute myocardial infarction, unstable angina, stable angina, other coronary heart diseases and congestive heart failure remain no obvious diferences and are of no statistic significance (P>0.05). In contrast, the quantitative valueof 25(OH) D in the control group are much higher and are of great statistic significance (t=19.75;P<0.05). Conclusions:There is a stro ng negative correlation between the concentration of vitamin D in the serum and the occurrence and progress of cardiovascular disease. Clinically, the quantitative testing of the vitamin D could be adopted to diagnose the cardiovascular disease.
