CAJ | 학술논문

目的：观察低氮低热卡肠外营养联合生长激素对胃肠肿瘤患者的治疗效果及安全有效性。方法选取2011年8月至2013年8月收治的胃肠肿瘤患者90例，随机分为观察组和对照组。对照组(45例)行低氮低热卡的肠外营养治疗，观察组(45例)行低氮低热卡的肠外营养联合生长激素治疗，对比两组患者手术相关物质代谢指标、术后恢复时间及术后并发症发生情况。结果观察组的白蛋白和转铁蛋白含量明显高于对照组（ P＜0.05），而血糖水平改善无显著性差异（ P＞0.05）；观察组的排气时间和住院时间以及体重下降的比例均小于对照组（ P＜0.05）；观察组治疗后并发症发生率、感染型并发症和非感染型并发症发生率均显著小于对照组（ P＜0.05）。结论低氮低热卡肠外营养联合生长激素能改善患者的能量代谢，加速患者的恢复时间并减少并发症，是快捷、有效、安全的胃肠肿瘤患者术后治疗方法。
목적：관찰저담저열잡장외영양연합생장격소대위장종류환자적치료효과급안전유효성。방법선취2011년8월지2013년8월수치적위장종류환자90례，수궤분위관찰조화대조조。대조조(45례)행저담저열잡적장외영양치료，관찰조(45례)행저담저열잡적장외영양연합생장격소치료，대비량조환자수술상관물질대사지표、술후회복시간급술후병발증발생정황。결과관찰조적백단백화전철단백함량명현고우대조조（ P＜0.05），이혈당수평개선무현저성차이（ P＞0.05）；관찰조적배기시간화주원시간이급체중하강적비례균소우대조조（ P＜0.05）；관찰조치료후병발증발생솔、감염형병발증화비감염형병발증발생솔균현저소우대조조（ P＜0.05）。결론저담저열잡장외영양연합생장격소능개선환자적능량대사，가속환자적회복시간병감소병발증，시쾌첩、유효、안전적위장종류환자술후치료방법。
Objective To observe the therapeutic effect of hyponitrogenic and hypocaloric parenteral nutrition combined with the hor-mone replacement therapy in treating gastrointestinal tumor. Methods 90 patients with gastrointestinal tumor in our hospital from Au-gust 2011 to August 2013 were selected as the research subjects. The patients were randomly assigned to the observation group and the control group. The control group ( 45 cases ) was treated by the hyponitrogenic and hypocaloric parenteral nutrition, while the obser-vation group ( 45 cases ) was performed the hyponitrogenic and hypocaloric parenteral nutrition combined with the hormone replacement therapy. The related metabolic indexes, postoperative recovery time and postoperative complications were analyzed and compared between the two groups. Results The contents of albumin ( ALB ) and transferrin ( TRF ) had the statistically significant difference between the observation group and the control group ( P < 0. 05 ) . But the blood sugar levels had no statistically significant difference between the two groups ( P > 0. 05 ) and had the comparability. The proportions of exhausting time, hospital stay and weight lose were lower than those in control group ( P < 0. 05 ) , the difference was statistically significant ( P < 0. 05 ) . The cases number of complication occurrence in the observation group was lower than that in the control group, the difference was statistically significant ( P < 0. 05 ) . Conclusion Hyponitrogenic and hypocaloric parenteral nutrition combined with the hormone replacement therapy can improve the patient ’ s energy metabolism, accelerate the recovery time, reduce complications and is a rapid and effective postoperative therapeutic method in the pa-tients with gastrointestinal tumor.