CAJ | 학술논문

目的：探讨肺动脉血流频谱特征在胎儿法洛四联症（TOF）诊断中的应用价值。方法选取21例肺动脉发育不良的TOF胎儿作为病例组，46例孕周基本相同的正常胎儿作为对照组，测量其肺动脉内径各参数和肺动脉主干血流频谱参数。结果病例组肺动脉主干血流频谱特征为：射血时间、加速时间和减速时间均缩短，流速时间积分缩小，与对照组相比差异有统计学意义（P<0.01）；峰值流速增加，肺动脉主干与主动脉最大血流速度比值增加，与对照组相比差异有统计学意义（P<0.01）；主动脉最大血流速度无明显增加，与对照组相比差异无统计学意义（P=0.22>0.05）。结论TOF胎儿的肺动脉主干血流频谱具有特征性表现，可为该病的诊断提供依据。
목적：탐토폐동맥혈류빈보특정재태인법락사련증（TOF）진단중적응용개치。방법선취21례폐동맥발육불량적TOF태인작위병례조，46례잉주기본상동적정상태인작위대조조，측량기폐동맥내경각삼수화폐동맥주간혈류빈보삼수。결과병례조폐동맥주간혈류빈보특정위：사혈시간、가속시간화감속시간균축단，류속시간적분축소，여대조조상비차이유통계학의의（P<0.01）；봉치류속증가，폐동맥주간여주동맥최대혈류속도비치증가，여대조조상비차이유통계학의의（P<0.01）；주동맥최대혈류속도무명현증가，여대조조상비차이무통계학의의（P=0.22>0.05）。결론TOF태인적폐동맥주간혈류빈보구유특정성표현，가위해병적진단제공의거。
Objective To analyze the effectiveness of application of the pulmonary artery flow spectrum features in diagnosis of TOF (Tetralogy of Fallot) fetuses. Methods Altogether 21 cases of TOF fetuses with pulmonary artery dysplasia were taken as Experiment Group; while, 46 cases of healthy fetuses in the similar pregnant weeks were selected as Control Group. The inner diameters of pulmonary arteries and the main pulmonary artery flow spectrum were measured in both groups. Results The features of the main pulmonary artery flow spectrum revealed in Experiment Group included shorter ACT (Acceleration Time), DT (Deceleration Time), ET (Ejection Time) and smaller VTI (Velocity-Time Integral) than those of Control Group, which were of statistical significance (P<0.01); moreover, the increased peak flow velocity and percentage between PVmax (Pulmonary Velocity Maximum) and AVmax (Artery Velocity Maximum) also showed statically significant differences between two groups (P<0.01). Compared to control group, the AVmax increased unobviously in experiment group and the difference was not significant (P=0.22>0.05). Conclusion The pulmonary artery flow spectrum of TOF fetuses could demonstrate its characteristic features and provide foundations for diagnosis of the disease.