白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2015年
4期
234-237
,共4页
宋晓婕%张建新%杜笑松%侯丽娜%辛磊%赵致楷%杨继虎%杨晓棠
宋曉婕%張建新%杜笑鬆%侯麗娜%辛磊%趙緻楷%楊繼虎%楊曉棠
송효첩%장건신%두소송%후려나%신뢰%조치해%양계호%양효당
颈部淋巴瘤%体层摄影术,X线计算机%灌注成像%宝石能谱成像%灌注参数%碘含量
頸部淋巴瘤%體層攝影術,X線計算機%灌註成像%寶石能譜成像%灌註參數%碘含量
경부림파류%체층섭영술,X선계산궤%관주성상%보석능보성상%관주삼수%전함량
Neck lymphoma%Tomography,x-ray computed%Perfusion imaging%Gem stone spectral imaging%Perfusion parameters%Iodine contents
目的 探讨能谱CT多期扫描颈部淋巴瘤计算所得的碘含量(IC)与CT灌注各参数的相关性及对淋巴瘤诊断的特异性及敏感性.方法 选取20例经病理证实的淋巴瘤患者,使用GE能谱CTPerfusion GSI序列同时获得能谱扫描的淋巴瘤动脉、静脉期IC与灌注扫描的血流量(BF)、血容量(BV)、平均通过时间(MTT)和表面通透性(PS)等灌注参数,进行相关性分析,通过受试者工作特征(ROC)曲线分析IC和各灌注参数的最佳诊断界点、敏感性、特异性.结果 能谱扫描的动脉期IC与各灌注参数BF、BV、MTT和PS的相关系数分别为0.200、0.302、0.013、0.148,静脉期IC与各灌注参数BF、BV、MTT和PS的相关系数分别为-0.109、-0.022、0.002、0.211,均无相关性(均P＞0.05),动脉期、静脉期IC的最佳诊断界点为14.51、21.23时,对颈部淋巴瘤有较高的敏感度和特异度.结论 能谱CT多期颈部淋巴瘤的IC有助于定性诊断淋巴瘤.
目的 探討能譜CT多期掃描頸部淋巴瘤計算所得的碘含量(IC)與CT灌註各參數的相關性及對淋巴瘤診斷的特異性及敏感性.方法 選取20例經病理證實的淋巴瘤患者,使用GE能譜CTPerfusion GSI序列同時穫得能譜掃描的淋巴瘤動脈、靜脈期IC與灌註掃描的血流量(BF)、血容量(BV)、平均通過時間(MTT)和錶麵通透性(PS)等灌註參數,進行相關性分析,通過受試者工作特徵(ROC)麯線分析IC和各灌註參數的最佳診斷界點、敏感性、特異性.結果 能譜掃描的動脈期IC與各灌註參數BF、BV、MTT和PS的相關繫數分彆為0.200、0.302、0.013、0.148,靜脈期IC與各灌註參數BF、BV、MTT和PS的相關繫數分彆為-0.109、-0.022、0.002、0.211,均無相關性(均P＞0.05),動脈期、靜脈期IC的最佳診斷界點為14.51、21.23時,對頸部淋巴瘤有較高的敏感度和特異度.結論 能譜CT多期頸部淋巴瘤的IC有助于定性診斷淋巴瘤.
목적 탐토능보CT다기소묘경부림파류계산소득적전함량(IC)여CT관주각삼수적상관성급대림파류진단적특이성급민감성.방법 선취20례경병리증실적림파류환자,사용GE능보CTPerfusion GSI서렬동시획득능보소묘적림파류동맥、정맥기IC여관주소묘적혈류량(BF)、혈용량(BV)、평균통과시간(MTT)화표면통투성(PS)등관주삼수,진행상관성분석,통과수시자공작특정(ROC)곡선분석IC화각관주삼수적최가진단계점、민감성、특이성.결과 능보소묘적동맥기IC여각관주삼수BF、BV、MTT화PS적상관계수분별위0.200、0.302、0.013、0.148,정맥기IC여각관주삼수BF、BV、MTT화PS적상관계수분별위-0.109、-0.022、0.002、0.211,균무상관성(균P＞0.05),동맥기、정맥기IC적최가진단계점위14.51、21.23시,대경부림파류유교고적민감도화특이도.결론 능보CT다기경부림파류적IC유조우정성진단림파류.
Objective To explore the correlation between iodine content (IC) calculated from gemstone spectral imaging scan and parameters of perfusion measured with perfusion CT,and to determine their sensitivities and specificities.Methods 20 patients with pathologically diagnosed as lymphoma received gemstone spectral imaging scan to get the parameters including blood flow (BF),blood volume (BV),mean transit time (MTT) and permeability surface (PS) from perfusion CT and IC from spectral CT.The relationship between IC and parameters was analyzed.Receiver operating characteristic (ROC) curve was performed to determine the cut-off values,sensitivities and specificities IC and parameters of perfusion.Results There were no correlations between arterial phase of IC (r =0.200,0.302,0.013,0.148,P ＞ 0.05) or venous phase of IC (r =-0.109,-0.022,0.002,0.211,P＞ 0.05) and parameters of perfusion (BF,BV,MTT and PS).When the cut-off value of IC was 14.51 and 21.23 in arterial phase and venous phase,respectively,sensitivities and specificities on the lymphoma of neck were high.Conclusion IC from spectral CT may contribute to judging the nature of neck lymph nodes.
