CAJ | 학술논문

目的：探讨双歧杆菌三联活菌片治疗儿童抗生素相关性腹泻(AAD)的临床疗效。方法将我院儿科收治的88例AAD患儿随机分为两组各44例，对照组患儿给予包括蒙脱石散及补液、维持电解质平衡等的常规治疗，观察组患儿在对照组治疗的基础上联合应用双歧杆菌三联活菌片治疗，观察两组患儿的临床疗效。结果观察组患儿的治疗总有效率为97.72%，明显高于对照组的86.36%，差异有统计学意义(P<0.05)；观察组患儿的腹泻持续时间及住院时间均明显短于对照组，差异均有显著统计学意义(P<0.01)。结论儿童抗生素相关性腹泻的治疗中加用双歧杆菌三联活菌片可快速恢复失调的肠道菌群，缩短患儿病程及住院时间。
목적：탐토쌍기간균삼련활균편치료인동항생소상관성복사(AAD)적림상료효。방법장아원인과수치적88례AAD환인수궤분위량조각44례，대조조환인급여포괄몽탈석산급보액、유지전해질평형등적상규치료，관찰조환인재대조조치료적기출상연합응용쌍기간균삼련활균편치료，관찰량조환인적림상료효。결과관찰조환인적치료총유효솔위97.72%，명현고우대조조적86.36%，차이유통계학의의(P<0.05)；관찰조환인적복사지속시간급주원시간균명현단우대조조，차이균유현저통계학의의(P<0.01)。결론인동항생소상관성복사적치료중가용쌍기간균삼련활균편가쾌속회복실조적장도균군，축단환인병정급주원시간。
Objective To investigate the efficacy of live combined bifidobacterium and lactobacillus tablets in the treatment of antibiotic-associated diarrhea (AAD) in children. Methods Eighty-eight children with AAD were randomly divided into two groups, with 44 children in each group. The control group were treated by rehydration, maintain electrolyte balance and montmorillonite powder and other conventional treatment, while the observation group was given additionally live combined bifidobacterium and lactobacillus tablets. The clinical efficacy were com-pared between the two groups. Results The total effective rate in the observation group was 97.72%%, which was significantly higher than that in the control group (86.36%), P<0.05. The duration of diarrhea and length of hospital stay in the observation group were significantly shorter than those in the control group, with statistically significant dif-ference (P<0.01). Conclusion Live combined bifidobacterium and lactobacillus tablets in the treatment of AAD in children can quickly restore intestinal flora, and shorten the duration of diarrhea and length of hospital stay.