CAJ | 학술논문

目的：了解常见21种人乳头瘤病毒(HPV)在海南地区的亚型分布、多重感染和不同年龄感染情况。方法使用PCR体外扩增和膜杂交法对2013年1~12月来我院就诊的10764例女性进行HPV分型检查。结果10764例样本中阳性率为19.38%，多重感染率为4.96%，25岁以下阳性率最高，各亚型检出率最高依次为52型、16型和58型，未检出43型。结论海南地区主要HPV感染亚型为52型、16型和58型，HPV感染有低龄化趋势。
목적：료해상견21충인유두류병독(HPV)재해남지구적아형분포、다중감염화불동년령감염정황。방법사용PCR체외확증화막잡교법대2013년1~12월래아원취진적10764례녀성진행HPV분형검사。결과10764례양본중양성솔위19.38%，다중감염솔위4.96%，25세이하양성솔최고，각아형검출솔최고의차위52형、16형화58형，미검출43형。결론해남지구주요HPV감염아형위52형、16형화58형，HPV감염유저령화추세。
Objective To investigate the genotypes distribution of 21 common human papillomavirus (HPV) in Hainan province, rate of multiple infections and infection rates among different age groups. Methods A total of 10 764 samples from females in Hainan were tested for 21 DNA types of HPV by PCR and film chip blot. Results The HPV positive rate was 19.38%. The multiple infection rate was 4.96%, and there was relatively high infection rate among females under 25 years old. Out of the 21 subtypes of HPV, HPV-52 was the most common subtype detected, followed by subtypes HPV-16 and HPV-58. HPV-43 was not detected. Conclusion The most prevalent HPV sub-types are HPV-52, HPV-16 and HPV-58 in Hainan province, and the highest rate of HPV infection is found in fe-males under 25 years old.