CAJ | 학술논문

肺癌干细胞（ lung cancer stem cell，LCSC）是肺组织中一小部分具有自我更新和增殖分化潜能，并具耐药功能的特定细胞群。它与肺癌的发生、进展、转移、耐药关系密切。本文对肺癌干细胞的起源、分选以及所涉及到的相关信号通路和标志物等方面进行综述，为未来肺癌的临床诊断及治疗提供新的思路。
폐암간세포（ lung cancer stem cell，LCSC）시폐조직중일소부분구유자아경신화증식분화잠능，병구내약공능적특정세포군。타여폐암적발생、진전、전이、내약관계밀절。본문대폐암간세포적기원、분선이급소섭급도적상관신호통로화표지물등방면진행종술，위미래폐암적림상진단급치료제공신적사로。
Lung cancer stem cell( LCSC),a small part of the lung tissue which has the ability of self-renewing and the potential of proliferation differentiation,is a specific cell population. It has a very close relationship with lung canc-erˊs occurring,progressing,transferring,drug resistance,and so on. This paper mainly the origin of lung cancer stem cells,their isolation,identification,related signaling pathways,and markers provide some new methods for the clinical diagnosis and treatment of lung cancer in the future.