CAJ | 학술논문

红曲霉中的γ-氨基丁酸（GABA）是一种功能性氨基酸。它是目前研究较为深入的一种重要的抑制性神经递质，具有多种生理活性。但是红曲霉 GABA 产量通常较低，使其工业化生产及应用受到限制。结合近年的研究成果，主要综述高产菌株选育、发酵条件和工艺优化、多菌种混合发酵、相关基因的研究来提高 GABA 产量的方法，旨在为提高红曲霉中γ-氨基丁酸产量提供相应的技术参考。
홍곡매중적γ-안기정산（GABA）시일충공능성안기산。타시목전연구교위심입적일충중요적억제성신경체질，구유다충생리활성。단시홍곡매 GABA 산량통상교저，사기공업화생산급응용수도한제。결합근년적연구성과，주요종술고산균주선육、발효조건화공예우화、다균충혼합발효、상관기인적연구래제고 GABA 산량적방법，지재위제고홍곡매중γ-안기정산산량제공상응적기술삼고。
γ-aminobutyric acid (GABA)from Monascus purpureus is a kind of functional amino acids. It is one of the most important inhibitory neurotransmitter studied deeply now,which has many physiological activities.However,the yield of GABA from Monascus purpureus is lower,which limits its industrial production and application.Summarize a series of methods used for improving the yield of GABA from Monascus purpureus,such as high-producing strain breeding,fermentation conditions and process optimization,multiple bacteria compound fermentation,related gene research. These methods could be used for improving the yield of GABA from Monascus purpureus.