创伤外科杂志
創傷外科雜誌
창상외과잡지
JOURNAL OF AUMATIC SURGERY
2015年
3期
260-262
,共3页
烧伤%生肤剂%烧伤膏%镇痛%消炎
燒傷%生膚劑%燒傷膏%鎮痛%消炎
소상%생부제%소상고%진통%소염
burns%skin regeneration agent%ointment%analgesia%anti-inflammation
目的：探讨烧伤生肤剂与美宝湿润烧伤软膏对烧伤患者的镇痛和消炎作用。方法采用随机数字表法将我院烧伤整形外科2012年8月～2014年4月收治的96例中度烧伤患者分为研究组和对照组各48例，研究组患者采用常规治疗结合烧伤生肤剂进行治疗，对照组采用美宝湿润烧伤软膏进行治疗。比较两组患者用药前、用药后第3、7天的疼痛、细胞炎性因子变化及疗效情况。结果研究组和对照组的视觉模拟评分（VAS）及C反应蛋白（CRP）、降钙素原（PCT）、肿瘤坏死因子-α（TNF-α）、白细胞介素-10（IL-10）、白细胞介素-6（IL-6）在治疗前比较差异均不显著（P＞0.05）；治疗后第3天的CRP、PCT、TNF-α、IL-10、IL-6值均低于对照组但差异均不显著（P＜0.05）；研究组第3天的VAS及第7天的VAS、CRP、PCT、TNF-α、IL-10、IL-6水平均显著低于对照组（ P＜0.05）。结论烧伤生肤剂对于缓解烧伤患者的疼痛、烧伤后炎症反应较美宝湿润烧伤软膏具有较好的临床效果。
目的：探討燒傷生膚劑與美寶濕潤燒傷軟膏對燒傷患者的鎮痛和消炎作用。方法採用隨機數字錶法將我院燒傷整形外科2012年8月～2014年4月收治的96例中度燒傷患者分為研究組和對照組各48例，研究組患者採用常規治療結閤燒傷生膚劑進行治療，對照組採用美寶濕潤燒傷軟膏進行治療。比較兩組患者用藥前、用藥後第3、7天的疼痛、細胞炎性因子變化及療效情況。結果研究組和對照組的視覺模擬評分（VAS）及C反應蛋白（CRP）、降鈣素原（PCT）、腫瘤壞死因子-α（TNF-α）、白細胞介素-10（IL-10）、白細胞介素-6（IL-6）在治療前比較差異均不顯著（P＞0.05）；治療後第3天的CRP、PCT、TNF-α、IL-10、IL-6值均低于對照組但差異均不顯著（P＜0.05）；研究組第3天的VAS及第7天的VAS、CRP、PCT、TNF-α、IL-10、IL-6水平均顯著低于對照組（ P＜0.05）。結論燒傷生膚劑對于緩解燒傷患者的疼痛、燒傷後炎癥反應較美寶濕潤燒傷軟膏具有較好的臨床效果。
목적：탐토소상생부제여미보습윤소상연고대소상환자적진통화소염작용。방법채용수궤수자표법장아원소상정형외과2012년8월～2014년4월수치적96례중도소상환자분위연구조화대조조각48례，연구조환자채용상규치료결합소상생부제진행치료，대조조채용미보습윤소상연고진행치료。비교량조환자용약전、용약후제3、7천적동통、세포염성인자변화급료효정황。결과연구조화대조조적시각모의평분（VAS）급C반응단백（CRP）、강개소원（PCT）、종류배사인자-α（TNF-α）、백세포개소-10（IL-10）、백세포개소-6（IL-6）재치료전비교차이균불현저（P＞0.05）；치료후제3천적CRP、PCT、TNF-α、IL-10、IL-6치균저우대조조단차이균불현저（P＜0.05）；연구조제3천적VAS급제7천적VAS、CRP、PCT、TNF-α、IL-10、IL-6수평균현저저우대조조（ P＜0.05）。결론소상생부제대우완해소상환자적동통、소상후염증반응교미보습윤소상연고구유교호적림상효과。
Objective To investigate the effect of skin regeneration agent and moist exposed burn ointment ( MEBO) on analgesia and anti-inflammation in burned patients.Methods A total of 96 cases of moderately burn-ed patients from Aug.2012 to Apr.2014 in our department were randomly divided into study group and control group with 48 cases in each group.Patients in the study group were treated with traditional method combined with skin re-generation agent and those in the control group were treated with MEBO.Conditions of pain and changes of inflam-matory factors and effects in the two groups before ointment usage,3 days after usage and 7 days after usage were compared.Results The differences of the VAS score,CRP,PCT,TNF-α,IL-10 and IL-6 between the study group and the control group before treatment were not significant( P>0.05);the values of CRP,PCT,TNF-α,IL-10,IL-6 three days after treatment were lower than the control group but the difference was not significant ( P<0.05 );the VAS score three days after treatment and VAS score,values of CRP,PCT,TNF-α,IL-10,IL-6 seven days after treat-ment were significantly lower than those of the control group(P<0.05).Conclusion Skin regeneration agent has better clinical effect than MEBO in relieving pains and inflammation for burned patients.
