CAJ | 학술논문

目的：观察醒脑静注射液联合护理干预治疗肝性脑病患者的临床疗效。方法选择2011年11月至2013年11月医院收治的肝性脑病患者160例，按照护理方式将其分为研究组与对照组，各80例。两组患者均给予醒脑静注射液治疗，对照组患者给予常规护理，研究组患者在对照组基础上实施护理干预，对比两组患者的护理效果、护理满意度评分、生活质量评分、苏醒时间、天门冬氨酸氨基转移酶（AST）、丙氨酸氨基转移酶（ALT）、白蛋白（Alb）、总胆红素（TBIL）等肝功能恢复情况。结果研究组意外风险发生率、Ⅲ期及以上肝性脑病发生率、肝性脑病复发率分别为3.75%，16.25%，6.25%，均显著低于对照组的17.50%，35.00%，18.75%（ P﹤0.05）。研究组护理满意度评分、生活质量评分分别为（92.85±6.38）分和（46.38±2.35）分，均显著高于对照组的（81.43±7.19）分和（37.53±3.22）分（ P﹤0.05）；研究组苏醒时间为（5.45±1.82）h，显著少于对照组的（15.33±2.49）h（ P﹤0.05）。研究组血清AST，ALT，Alb，TBIL水平分别为（84.32±50.18）U/L，（75.34±51.52）U/L，（98.22±62.33）g/L，（72.46±41.28）μmol/L，分别显著低于对照组的（123.47±70.17）U/L，（95.46±43.53）U/L，（119.79±62.15）g/L，（92.67±40.09）μmol/L（ P﹤0.05）。结论采用醒脑静注射液联合护理干预治疗肝性脑病，不仅可降低Ⅲ期及以上肝性脑病和意外风险的发生率，减少复发率，而且对患者苏醒时间、肝功能的恢复均可起到辅助作用，同时还能提高患者的生活质量，改善预后，效果显著。
목적：관찰성뇌정주사액연합호리간예치료간성뇌병환자적림상료효。방법선택2011년11월지2013년11월의원수치적간성뇌병환자160례，안조호리방식장기분위연구조여대조조，각80례。량조환자균급여성뇌정주사액치료，대조조환자급여상규호리，연구조환자재대조조기출상실시호리간예，대비량조환자적호리효과、호리만의도평분、생활질량평분、소성시간、천문동안산안기전이매（AST）、병안산안기전이매（ALT）、백단백（Alb）、총담홍소（TBIL）등간공능회복정황。결과연구조의외풍험발생솔、Ⅲ기급이상간성뇌병발생솔、간성뇌병복발솔분별위3.75%，16.25%，6.25%，균현저저우대조조적17.50%，35.00%，18.75%（ P﹤0.05）。연구조호리만의도평분、생활질량평분분별위（92.85±6.38）분화（46.38±2.35）분，균현저고우대조조적（81.43±7.19）분화（37.53±3.22）분（ P﹤0.05）；연구조소성시간위（5.45±1.82）h，현저소우대조조적（15.33±2.49）h（ P﹤0.05）。연구조혈청AST，ALT，Alb，TBIL수평분별위（84.32±50.18）U/L，（75.34±51.52）U/L，（98.22±62.33）g/L，（72.46±41.28）μmol/L，분별현저저우대조조적（123.47±70.17）U/L，（95.46±43.53）U/L，（119.79±62.15）g/L，（92.67±40.09）μmol/L（ P﹤0.05）。결론채용성뇌정주사액연합호리간예치료간성뇌병，불부가강저Ⅲ기급이상간성뇌병화의외풍험적발생솔，감소복발솔，이차대환자소성시간、간공능적회복균가기도보조작용，동시환능제고환자적생활질량，개선예후，효과현저。
Objective To observe the clinical effects of Xingnaojing Injection combined with nursing intervention in treating the patients with hepatic encephalopathy. Methods 160 cases of hepatic encephalopathy in the hospital from November 2011 to November 2013 were selected and divided into the study group and the control group according to the nursing mode,80 cases in each group. The two groups were treated with Xingnaojing Injection. The control group received the routine nursing,while on this basis the study group was implemented the nursing intervention. The nursing effect,nursing satisfaction scores,life quality score,recovery time and liver function re-covery situation including aspartate aminotransferase(AST),alanine aminotransferase(ALT),albumin(Alb),total bilirubin(TBIL)were ob-served and compared between the two groups. Results The occurrence rate of accident risk,occurrence rate of hepatic encephalopathy stage Ⅲ or over and recurrent rate of hepatic encephalopathy in the study group were 3. 75%,16. 25% and 6. 25% respectively,which were significantly lower than 17. 50%,35. 00% and 18. 75% in the control group( P ﹤ 0. 05). The nursing satisfaction scores and life quality scores in the study group were(92. 85 ± 6. 38)points and (46. 38 ± 2. 35)points,which were significantly higher than (81. 43 ± 7. 19) points and(37. 53 ± 3. 22)points in the control group( P ﹤ 0. 05);the recovery time in the study group was(5. 45 ± 1. 82)h,which was significantly shorter than(15. 33 ± 2. 49)h in the control group( P ﹤ 0. 05). Serum AST,ALT,Alb and TBIL levels in the study group were(84. 32 ± 50. 18)U/L,(75. 34 ± 51. 52)U/L,(98. 22 ± 62. 33)g/L and(72. 46 ± 41. 28)μmol/L,which were significantly lower than (123. 47 ± 70. 17)U/L,(95. 46 ± 43. 53)U/L,(119. 79 ± 62. 15)g/L and(92. 67 ± 40. 09)μmol/L in the control group( P ﹤ 0. 05). Conclusion Adopting Xingnaojing Injection combined with nursing intervention for treating hepatic encephalopathy can not only de-crease the occurrence rate of hepatic encephalopathy stage Ⅲ or over and accident risk,reduce the recurrence rate,but also has the auxiliary effect in the recovery time and liver function recovery,at the same time increase the patient's life quality,improve the progno-sis. It has significant effect.