CAJ | 학술논문

目的：观察依帕司他用于促进糖尿病足伤口愈合的临床效果。方法：将60例糖尿病足病人随机分为观察组与对照组，每组各30例，两组患者均给予胰岛素、控制感染、改善微循环、伤口常规冲洗换药等治疗，观察组在此基础上加用依帕司他，疗程均为2个月，比较两组患者总有效率以及治疗后伤口面积缩小情况、伤口愈合时间的差异。结果：观察组总有效率为86．7％（26／30），伤口面积缩小（81．6±6．7）％，伤口愈合时间为（24．5±4．3）d；对照组总有效率为63．3％（19／30），伤口面积缩小（52．4±6．2）％，伤口愈合时间为（32．7±4．8）d，组间比较差异均有统计学意义（ P ＜0．05）。结论：依帕司他用于促进糖尿病足伤口愈合效果明显。
목적：관찰의파사타용우촉진당뇨병족상구유합적림상효과。방법：장60례당뇨병족병인수궤분위관찰조여대조조，매조각30례，량조환자균급여이도소、공제감염、개선미순배、상구상규충세환약등치료，관찰조재차기출상가용의파사타，료정균위2개월，비교량조환자총유효솔이급치료후상구면적축소정황、상구유합시간적차이。결과：관찰조총유효솔위86．7％（26／30），상구면적축소（81．6±6．7）％，상구유합시간위（24．5±4．3）d；대조조총유효솔위63．3％（19／30），상구면적축소（52．4±6．2）％，상구유합시간위（32．7±4．8）d，조간비교차이균유통계학의의（ P ＜0．05）。결론：의파사타용우촉진당뇨병족상구유합효과명현。
Objective:To investigate the effect of epalrestat on promoting wound healing in patients with diabetic foot .Methods:60 cases of diabetic foot were randomly divided into the control group and the observation group , with 30 cases in each group.Both groups were given the treat-ment of insulin, controlling infection, improving minicirculation, and routine rinsing and dressing change, but epalrestat was only administered ad-ditionally to the observation group, which lasted for 2 months.The total effective rate, the reduction situation of wound area and wound healing time were compared between the two groups.Results:The total effective rate, the reduction of wound area and wound healing time were significantly bet-ter in the observation group than those in the control group (86.7% vs.63.3%, (81.6 ±6.7)% vs.(52.4 ±6.2)%, (24.5 ±4.3) d vs. (32.7 ±4.8)d, P <0.05).Conclusion:There is a significant effect of epalrestat on promoting wound healing in patients with diabetic foot.