包头医学院学报
包頭醫學院學報
포두의학원학보
JOURNAL OF BAOTOU MEDICAL COLLEGE
2015年
5期
29-30
,共2页
新生儿%缺氧缺血性脑病%早期肠内营养治疗%肠外营养治疗
新生兒%缺氧缺血性腦病%早期腸內營養治療%腸外營養治療
신생인%결양결혈성뇌병%조기장내영양치료%장외영양치료
Newborns%Hypoxic ischemic encephalopathy%Early enteral nutrition therapy%Parenteral nutrition therapy
目的：研究早期肠内营养联合肠外营养支持对新生儿缺氧缺血性脑病患儿的治疗效果。方法：选择2010年5月至2012年5月我科收治的新生儿缺氧缺血性脑病患者36例，随机分为对照组和观察组各18例，对照组采用单纯肠外营养支持，观察组则采用早期肠内营养联合肠外营养支持，比较两组痊愈率、好转率、未愈率及死亡率，并对两组患者在治疗前后分别进行新生儿行为测定（ neo-natal behavioral neurological assessment，NBNA）检查。结果：观察组显效率（61．11％）、总有效率（94．44％）均高于对照组（27．78％、66．67％）（χ2显效率＝4．05， P ＜0．05；χ2总有效率＝4．4334， P ＜0．05）；观察组治疗1周、2周、3周时及3周后NBNA评分均高于对照组（ t1周＝4．6209、P ＜0．01， t 2周＝6．6426、P ＜0．01， t 3周＝5．1985、P ＜0．01， t 3周后＝7．7978、P ＜0．01）。结论：新生儿缺氧缺血性脑病患者接受早期肠内营养联合肠外营养支持治疗后，能有效减少神经系统后遗症的发生率，疗效显著，具有较高的临床推广价值。
目的：研究早期腸內營養聯閤腸外營養支持對新生兒缺氧缺血性腦病患兒的治療效果。方法：選擇2010年5月至2012年5月我科收治的新生兒缺氧缺血性腦病患者36例，隨機分為對照組和觀察組各18例，對照組採用單純腸外營養支持，觀察組則採用早期腸內營養聯閤腸外營養支持，比較兩組痊愈率、好轉率、未愈率及死亡率，併對兩組患者在治療前後分彆進行新生兒行為測定（ neo-natal behavioral neurological assessment，NBNA）檢查。結果：觀察組顯效率（61．11％）、總有效率（94．44％）均高于對照組（27．78％、66．67％）（χ2顯效率＝4．05， P ＜0．05；χ2總有效率＝4．4334， P ＜0．05）；觀察組治療1週、2週、3週時及3週後NBNA評分均高于對照組（ t1週＝4．6209、P ＜0．01， t 2週＝6．6426、P ＜0．01， t 3週＝5．1985、P ＜0．01， t 3週後＝7．7978、P ＜0．01）。結論：新生兒缺氧缺血性腦病患者接受早期腸內營養聯閤腸外營養支持治療後，能有效減少神經繫統後遺癥的髮生率，療效顯著，具有較高的臨床推廣價值。
목적：연구조기장내영양연합장외영양지지대신생인결양결혈성뇌병환인적치료효과。방법：선택2010년5월지2012년5월아과수치적신생인결양결혈성뇌병환자36례，수궤분위대조조화관찰조각18례，대조조채용단순장외영양지지，관찰조칙채용조기장내영양연합장외영양지지，비교량조전유솔、호전솔、미유솔급사망솔，병대량조환자재치료전후분별진행신생인행위측정（ neo-natal behavioral neurological assessment，NBNA）검사。결과：관찰조현효솔（61．11％）、총유효솔（94．44％）균고우대조조（27．78％、66．67％）（χ2현효솔＝4．05， P ＜0．05；χ2총유효솔＝4．4334， P ＜0．05）；관찰조치료1주、2주、3주시급3주후NBNA평분균고우대조조（ t1주＝4．6209、P ＜0．01， t 2주＝6．6426、P ＜0．01， t 3주＝5．1985、P ＜0．01， t 3주후＝7．7978、P ＜0．01）。결론：신생인결양결혈성뇌병환자접수조기장내영양연합장외영양지지치료후，능유효감소신경계통후유증적발생솔，료효현저，구유교고적림상추엄개치。
Objective:To assess the curative effect of early enteral and parenteral nutrition support therapy in the treatment of neonatal hypoxic-ischemic encephalopathy.Methods:36 cases of neonatal hypoxic-ischemic encephalopathy treated in our hospital from May 2010 to May 2012 were randomly divided into the control group(18 cases) and observation group(18 cases).The control group was given a simple parenteral nutri-tional support and the observation group was given early enteral nutrition combined with parenteral nutrition support .Cure rate, improvement rate, unhealing rate and death rate were compared between the two groups, with neonatal behavioral neurological assessment (NBNA) given to the pa-tients in the two groups before and after treatment of examination .Results:The effective rate and the total efficiency were (61.11 %) and (94.44%),respectively, significantly higher than those (27.78% and 66.67%) in the control group (χ2 =4.05, P <0.05; χ2 =4.4334, P <0. 05).NBNA scores in the observation group one week, two weeks and three weeks after the treatment were significantly higher than those in the control group ( t =4.6209, P <0.01;t =6.6426, P <0.01;t =5.1985, P <0.01;t =7.7978, P <0.01).Conclusion:Early enteral nu-trition and parenteral nutrition support therapy for treating neonatal hypoxic -ischemic encephalopathy can effectively reduce the incidence of neuro-logical sequelae, with a significant curative effect and a great clinical value .
