中国实用神经疾病杂志
中國實用神經疾病雜誌
중국실용신경질병잡지
CHINESE JOURNAL OF PRACTICAL NERVOUS DISEASES
2015年
10期
27-28
,共2页
脑膜癌病%脑脊液检查%脑脊液
腦膜癌病%腦脊液檢查%腦脊液
뇌막암병%뇌척액검사%뇌척액
Meningeal carcinomatosis%Cerebrospinal fluid examination%Cerebrospinal
目的：探讨脑膜癌病患者脑脊液常规及生化改变特点，评价其对脑膜癌病的诊断价值。方法回顾性分析92例脑膜癌病患者的临床及脑脊液检查资料，总结其脑脊液压力、白细胞数、葡萄糖、蛋白和氯化物含量的分布规律。结果脑脊液常规生化检查异常者95.60％，主要表现为糖降低（73.03％），其中≤1.0 mmol／L 者占14.61％；其次为颅内压升高（71.76％），最高可达400 cm H2 O ，其中＞300 cm H2 O者占18.82％；蛋白升高（70.79％），其中＞1 g／L者占39.33％；氯化物降低（52.81％），均未低于100 mmol／L ；WBC升高不明显，54例（6136％）患者WBC≤10×106／L ，其余34例WBC升高的患者中，29例（85.29％） WBC≤100×106／L。结论脑膜癌病患者脑脊液常规生化检查异常率高，颅内压及蛋白不同程度显著升高，葡萄糖降低，白细胞升高和氯化物降低不明显是其主要特点。
目的：探討腦膜癌病患者腦脊液常規及生化改變特點，評價其對腦膜癌病的診斷價值。方法迴顧性分析92例腦膜癌病患者的臨床及腦脊液檢查資料，總結其腦脊液壓力、白細胞數、葡萄糖、蛋白和氯化物含量的分佈規律。結果腦脊液常規生化檢查異常者95.60％，主要錶現為糖降低（73.03％），其中≤1.0 mmol／L 者佔14.61％；其次為顱內壓升高（71.76％），最高可達400 cm H2 O ，其中＞300 cm H2 O者佔18.82％；蛋白升高（70.79％），其中＞1 g／L者佔39.33％；氯化物降低（52.81％），均未低于100 mmol／L ；WBC升高不明顯，54例（6136％）患者WBC≤10×106／L ，其餘34例WBC升高的患者中，29例（85.29％） WBC≤100×106／L。結論腦膜癌病患者腦脊液常規生化檢查異常率高，顱內壓及蛋白不同程度顯著升高，葡萄糖降低，白細胞升高和氯化物降低不明顯是其主要特點。
목적：탐토뇌막암병환자뇌척액상규급생화개변특점，평개기대뇌막암병적진단개치。방법회고성분석92례뇌막암병환자적림상급뇌척액검사자료，총결기뇌척액압력、백세포수、포도당、단백화록화물함량적분포규률。결과뇌척액상규생화검사이상자95.60％，주요표현위당강저（73.03％），기중≤1.0 mmol／L 자점14.61％；기차위로내압승고（71.76％），최고가체400 cm H2 O ，기중＞300 cm H2 O자점18.82％；단백승고（70.79％），기중＞1 g／L자점39.33％；록화물강저（52.81％），균미저우100 mmol／L ；WBC승고불명현，54례（6136％）환자WBC≤10×106／L ，기여34례WBC승고적환자중，29례（85.29％） WBC≤100×106／L。결론뇌막암병환자뇌척액상규생화검사이상솔고，로내압급단백불동정도현저승고，포도당강저，백세포승고화록화물강저불명현시기주요특점。
Objective To investigate the routine and biochemical features of cerebrospinal fluid (CSF) in meningeal carcino‐matosis.Methods 92 cases with meningeal carcinomatosis were selected retrospectively. We analyzed the distribution of CSF pressure ,leukocyte count ,glucose ,protein and chloride content.Results The abnormal routine and biochemical examination of cerebrospinal fluid (CSF) accounted for 95.60% ,among which mainly showed glucose reduction(73.03% ) with 14.61% of them being less than 1.0 mmol/L ,high intracranial pressure (71.76% ) ranged from 180 to 400 mmH2 O with 18.82% of them being more than 300 mmH2 O ,elevated protein concentration (70.79% ) with 39.33% of them being more than 1 g/L ,low chloride concentration (52.81% ) with none being less than 100 mmol/L. Lymphocyte count was normal (less than 10 × 106/L) in 54 patients (61.36% ) ,abnormal in the rest 34 patients ,29 patients (85.29% ) of them just had slightly increased lympho‐cytes (less than 100 × 106/L).Conclusion The abnormal rate of routine and biochemical examination of CSF is high in patients with meningeal carcinomatosis. The high intracranial pressure and protein ,low glucose ,lymphocyte count and chloride concen‐tration reduced but not obviously are main characteristics.
