CAJ | 학술논문

目的：探讨特发性急性脊髓炎与多发性硬化预后的关系。方法2011‐09—2013‐08选择在我院诊治的140例多发性硬化与60例特发性急性脊髓炎患者，均进行了流行病学、影像学与实验室检测，同时给予对症干预，观察预后与生活质量状况。结果2组的性别、年龄、病程、临床表现、神经功能状况（EDSS）评分与体重指数（BMI）值对比差异无统计学意义（P＞0.05）。脊髓炎组的头颅MRI异常率、NMO‐IgG抗体阳性率、视觉诱发电位异常率高于多发性硬化组，而血清尿酸含量低于多发性硬化组，差异均有统计学意义（ P＜0.05）。脊髓炎组与多发性硬化组的有效率分别为96.7％与97.1％，组间对比差异无统计学意义（P＞0.05）。治疗后脊髓炎组的躯体、心理与社会评分都明显低于对照组，差异有统计学意义（P＜0.05）。结论特发性急性脊髓炎与多发性硬化在临床影像学与实验室检测指标对比有明显差异，对预后生活质量有一定影响，要积极给予对症干预。
목적：탐토특발성급성척수염여다발성경화예후적관계。방법2011‐09—2013‐08선택재아원진치적140례다발성경화여60례특발성급성척수염환자，균진행료류행병학、영상학여실험실검측，동시급여대증간예，관찰예후여생활질량상황。결과2조적성별、년령、병정、림상표현、신경공능상황（EDSS）평분여체중지수（BMI）치대비차이무통계학의의（P＞0.05）。척수염조적두로MRI이상솔、NMO‐IgG항체양성솔、시각유발전위이상솔고우다발성경화조，이혈청뇨산함량저우다발성경화조，차이균유통계학의의（ P＜0.05）。척수염조여다발성경화조적유효솔분별위96.7％여97.1％，조간대비차이무통계학의의（P＞0.05）。치료후척수염조적구체、심리여사회평분도명현저우대조조，차이유통계학의의（P＜0.05）。결론특발성급성척수염여다발성경화재림상영상학여실험실검측지표대비유명현차이，대예후생활질량유일정영향，요적겁급여대증간예。
Objective To observe the relationship of prognosis between idiopathic acute myelitis and multiple sclerosis.Methods 140 cases with multiple sclerosis and 60 cases with idiopathic acute myelitis treated in our hospital from September 2011 to August 2013 were selected ,which received the detection of epidemiology ,iconography ,laboratory and were given symptomatic intervention. The prognosis and life quality were observed. Results The differences of sex ,age ,course of dis‐ease ,clinical manifestation ,EDSS score and BMI value between two groups had no statistical significance (P>0.05). The ab‐normal rates of head by MRI ,positive rate of NMO‐IgG antibody and abnormal rate of visual evoked potential in the myelitis group were evidently higher than those in the multiple sclerosis group ,and value of serum uric acid in the myelitis group was significantly lower compared with the multiple sclerosis group ,which had a statistical significance (P<0.05). The effective rates of the myelitis group and the multiple sclerosis group respective were 96.7% and 97.1% ,with no statistical differences (P>0.05). After treatment ,scores of the body ,psychology and society in the myelitis group were evidently lower than those in the multiple sclerosis group ,which showed statistical significance (P< 0.05). Conclusion Idiopathic acute myelitis and multiple sclerosis have evident differences for clinical and radiological diagnosis and laboratory detection indicator ,which has an influence on life quality. The patients should receive symptomatic intervention positively.