安徽医科大学学报
安徽醫科大學學報
안휘의과대학학보
ACTA UNIVERSITY MEDICINALIS ANHUI
2015年
5期
711-712,713
,共3页
黄姗姗%徐文华%马腾飞%肖芳莉%刘衍钊%王烈成%王元银
黃姍姍%徐文華%馬騰飛%肖芳莉%劉衍釗%王烈成%王元銀
황산산%서문화%마등비%초방리%류연쇠%왕렬성%왕원은
三叉神经痛%白介素-1β%白介素-6%肿瘤坏死因子-α%酶联免疫吸附试验
三扠神經痛%白介素-1β%白介素-6%腫瘤壞死因子-α%酶聯免疫吸附試驗
삼차신경통%백개소-1β%백개소-6%종류배사인자-α%매련면역흡부시험
trigeminal neuralgia%interleukin-1β%interleukin-6%tumor necrosis factor-α%ELISA
收集30例三叉神经痛(TN)患者、17例恶性肿瘤患者、17例普通炎症患者及20例健康患者空腹静脉血,ELISA法检测血清中白介素-1β(IL-1β)、白介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)的表达水平。 TN 组患者血清中 IL-1β、IL-6、TNF-α的表达水平均高于健康对照组,差异有统计学意义(P <0．05)；而与恶性肿瘤组和普通炎症组比较,差异无统计学意义。 IL-1β、IL-6、TNF-α炎症因子与 TN 发病有一定关联。
收集30例三扠神經痛(TN)患者、17例噁性腫瘤患者、17例普通炎癥患者及20例健康患者空腹靜脈血,ELISA法檢測血清中白介素-1β(IL-1β)、白介素-6(IL-6)和腫瘤壞死因子-α(TNF-α)的錶達水平。 TN 組患者血清中 IL-1β、IL-6、TNF-α的錶達水平均高于健康對照組,差異有統計學意義(P <0．05)；而與噁性腫瘤組和普通炎癥組比較,差異無統計學意義。 IL-1β、IL-6、TNF-α炎癥因子與 TN 髮病有一定關聯。
수집30례삼차신경통(TN)환자、17례악성종류환자、17례보통염증환자급20례건강환자공복정맥혈,ELISA법검측혈청중백개소-1β(IL-1β)、백개소-6(IL-6)화종류배사인자-α(TNF-α)적표체수평。 TN 조환자혈청중 IL-1β、IL-6、TNF-α적표체수평균고우건강대조조,차이유통계학의의(P <0．05)；이여악성종류조화보통염증조비교,차이무통계학의의。 IL-1β、IL-6、TNF-α염증인자여 TN 발병유일정관련。
Fasting venous blood of 30 trigeminal neuralgia (TN) patients, 17 cancer patients, 17 patients with general inflammation and 20 healthy people were enrolled in this study. The levels of IL-1β, IL-6 and TNF-α in se-rum were detected by ELISA. The serum levels of IL-1β, IL-6 and TNF-α in the TN group were significantly higher than those in the healthy group (P < 0. 05); however there were no significant differences with the cancer and in-flammatory patients group. The cytokines IL-1β, IL-6 and TNF-α are related with the pathogenesis of TN.
