CAJ | 학술논문

目的：探究替罗非班联合重组人脑利钠肽治疗急性心肌梗死伴心衰患者的临床疗效和安全性。方法选取2010年1月—2014年10月在该院接受治疗的150例急性心肌梗死伴心力衰竭患者为研究对象，将其随机分为实验组、观察组和对照组，每组平均50例，对照组仅给予单纯血栓抽吸治疗，观察组给予血管抽吸和替罗非班治疗，实验组给予血管抽吸、替罗非班联合重组人脑利钠肽治疗，分析三组患者的临床疗效。结果经过相应的治疗后，实验组术后梗死相关血管的TIMI3级血流均显著高于观察组和对照组，且与观察组和对照组之间的差异均具有统计学意义(<0.05)；实验组患者的治疗总有效率也明显高于其他两组(<0.05)。结论实验组所用的替罗非班联合重组人脑利钠肽治疗急性心肌梗死伴心衰的临床效果更佳，值得在临床治疗中推广使用。
목적：탐구체라비반연합중조인뇌리납태치료급성심기경사반심쇠환자적림상료효화안전성。방법선취2010년1월—2014년10월재해원접수치료적150례급성심기경사반심력쇠갈환자위연구대상，장기수궤분위실험조、관찰조화대조조，매조평균50례，대조조부급여단순혈전추흡치료，관찰조급여혈관추흡화체라비반치료，실험조급여혈관추흡、체라비반연합중조인뇌리납태치료，분석삼조환자적림상료효。결과경과상응적치료후，실험조술후경사상관혈관적TIMI3급혈류균현저고우관찰조화대조조，차여관찰조화대조조지간적차이균구유통계학의의(<0.05)；실험조환자적치료총유효솔야명현고우기타량조(<0.05)。결론실험조소용적체라비반연합중조인뇌리납태치료급성심기경사반심쇠적림상효과경가，치득재림상치료중추엄사용。
Objective To explore the clinical efficacy of tirofiban for Luo combined with recombinant human brain natriuretic peptide treatment.Methods Select 150 cases of patients in our hospital from 2010 Junuary to 2014 Octobor with heart failure with acute myocardial infarction (mi) as the research object. Control group only for pure thrombus suction treatment, observation group was given for class had vascular suction and treatment, the experimental group gives blood pump, for class had combined therapy with recombinant human brain natriuretic peptide and clinical therapeutic effect of three groups of patients were retrospectively analyzed. Results Compared with the observation group and control group, experimental group patients were significantly higher total effective treatment( <0.05).Conclusion The experimental group effect is remarkable, it is used widely in clinical treatment in the future.