CAJ | 학술논문

目的：探究高尿酸血症（HUA）与颈动脉粥样硬化（CAS）之间的相关性。方法选取我院收治的90例高尿酸血症患者为实验组，90例尿酸正常者为对照组，比较2组患者的血压、体重指数（BM I）、高密度脂蛋白、尿白蛋白排泄率、颈动脉内膜中层厚度最大值（最大IMT）、颈动脉内膜中层厚度平均值（平均IMT）等方面进行比较。计算2组患者的颈动脉粥样硬化发生率。结果实验组患者的体重指数、收缩压、颈动脉内膜中层厚度平均值和最大值高于对照组，高密度脂蛋白低于对照组，差异有统计学意义（ P＜0.05）。实验组中颈动脉粥样硬化的发生率67.78％高于对照组的13.33％，差异有统计学意义（P＜0.05）。结论高尿酸血症在颈动脉粥样硬化进程中起直接和（或）间接作用，应在临床中得到重视。
목적：탐구고뇨산혈증（HUA）여경동맥죽양경화（CAS）지간적상관성。방법선취아원수치적90례고뇨산혈증환자위실험조，90례뇨산정상자위대조조，비교2조환자적혈압、체중지수（BM I）、고밀도지단백、뇨백단백배설솔、경동맥내막중층후도최대치（최대IMT）、경동맥내막중층후도평균치（평균IMT）등방면진행비교。계산2조환자적경동맥죽양경화발생솔。결과실험조환자적체중지수、수축압、경동맥내막중층후도평균치화최대치고우대조조，고밀도지단백저우대조조，차이유통계학의의（ P＜0.05）。실험조중경동맥죽양경화적발생솔67.78％고우대조조적13.33％，차이유통계학의의（P＜0.05）。결론고뇨산혈증재경동맥죽양경화진정중기직접화（혹）간접작용，응재림상중득도중시。
Objective To explore the correlation between hyperuricemia and carotid atherosclerosis (CAS).Methods 90 cases with hyperuricemia in our hospital were selected as the experimental group ,90 cases with non‐hyperuricemia were select‐ed as the control group.And blood pressure ,body mass index (BMI) ,high‐density lipoprotein cholesterol (HDL‐C) ,urinary albumin excretion rate ,the maximum value of carotid intima‐media thickness (Max‐IMT) ,carotid intima‐media thickness on average(a‐IMT) were detected and compared in two groups. The incidence of carotid atherosclerosis was calculated in two groups.Results The body mass index ,systolic blood pressure and Max‐IMT and a‐IMT in experimental group were signifi‐cantly higher than those in control group ,while high‐density lipoprotein cholesterol (HDL‐C) was lower in experimental group (P<0.05). The incidence of carotid atherosclerosis in the experimental group (67.18% ) was higher than that in the control group(14.44% ) ,with a significant difference (P< 0.05). Conclusion Hyperuricemia has a direct or indirect role in the process of carotid artery atherosclerosis ,which should be paid more attention.