中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2015年
5期
406-410
,共5页
汪晓翠%杨斌%沈丽伟%杨广娥%叶小飞%张志明
汪曉翠%楊斌%瀋麗偉%楊廣娥%葉小飛%張誌明
왕효취%양빈%침려위%양엄아%협소비%장지명
注意网络%伴中央颞区棘波的儿童良性癫痫
註意網絡%伴中央顳區棘波的兒童良性癲癇
주의망락%반중앙섭구극파적인동량성전간
Attention networks%Benign epilepsy children with centrotemporal spikes
目的 研究伴中央颞区棘波的儿童良性癫痫(BECT)患者注意网络的损害情况.方法 运用Fan设计的注意网络测试工具,对已确诊的75例BECT患儿(BECT组)和75名健康儿童(对照组)分别进行注意网络检查.结果 BECT组注意网络检查正确率(95.77％±5.63％)低于对照组(98.55％±1.80％),差异有统计学意义(t =4.063,P＜0.05);BECT组注意网络检查总平均反应时[(946.87±199.82) ms]显著长于对照组[(729.00±146.75) ms],差异有统计学意义(t=-7.611,P ＜0.05).BECT组的定向网络效率[29(12,56) ms]低于对照组[51(21,78) ms],差异有统计学意义(Z=-2.771,P=0.006);执行功能网络效率[80(50,105) ms]高于对照组[57(25,88) ms],差异有统计学意义(Z=-2.146,P=0.032);两组间警觉网络效率差异无统计学意义(P＞0.05).非条件Logistic回归分析结果显示,发病年龄是影响患儿注意网络检查正确率和总平均反应时的相对独立危险因素(分别为OR=1.830,95％ CI1.193～2.807,P=0.006和OR=1.635,95％ CI 1.176～2.275,P=0.003).结论 BECT患儿存在注意网络损害,且癫痫发病年龄是影响患儿注意网络水平的危险因素.
目的 研究伴中央顳區棘波的兒童良性癲癇(BECT)患者註意網絡的損害情況.方法 運用Fan設計的註意網絡測試工具,對已確診的75例BECT患兒(BECT組)和75名健康兒童(對照組)分彆進行註意網絡檢查.結果 BECT組註意網絡檢查正確率(95.77％±5.63％)低于對照組(98.55％±1.80％),差異有統計學意義(t =4.063,P＜0.05);BECT組註意網絡檢查總平均反應時[(946.87±199.82) ms]顯著長于對照組[(729.00±146.75) ms],差異有統計學意義(t=-7.611,P ＜0.05).BECT組的定嚮網絡效率[29(12,56) ms]低于對照組[51(21,78) ms],差異有統計學意義(Z=-2.771,P=0.006);執行功能網絡效率[80(50,105) ms]高于對照組[57(25,88) ms],差異有統計學意義(Z=-2.146,P=0.032);兩組間警覺網絡效率差異無統計學意義(P＞0.05).非條件Logistic迴歸分析結果顯示,髮病年齡是影響患兒註意網絡檢查正確率和總平均反應時的相對獨立危險因素(分彆為OR=1.830,95％ CI1.193～2.807,P=0.006和OR=1.635,95％ CI 1.176～2.275,P=0.003).結論 BECT患兒存在註意網絡損害,且癲癇髮病年齡是影響患兒註意網絡水平的危險因素.
목적 연구반중앙섭구극파적인동량성전간(BECT)환자주의망락적손해정황.방법 운용Fan설계적주의망락측시공구,대이학진적75례BECT환인(BECT조)화75명건강인동(대조조)분별진행주의망락검사.결과 BECT조주의망락검사정학솔(95.77％±5.63％)저우대조조(98.55％±1.80％),차이유통계학의의(t =4.063,P＜0.05);BECT조주의망락검사총평균반응시[(946.87±199.82) ms]현저장우대조조[(729.00±146.75) ms],차이유통계학의의(t=-7.611,P ＜0.05).BECT조적정향망락효솔[29(12,56) ms]저우대조조[51(21,78) ms],차이유통계학의의(Z=-2.771,P=0.006);집행공능망락효솔[80(50,105) ms]고우대조조[57(25,88) ms],차이유통계학의의(Z=-2.146,P=0.032);량조간경각망락효솔차이무통계학의의(P＞0.05).비조건Logistic회귀분석결과현시,발병년령시영향환인주의망락검사정학솔화총평균반응시적상대독립위험인소(분별위OR=1.830,95％ CI1.193～2.807,P=0.006화OR=1.635,95％ CI 1.176～2.275,P=0.003).결론 BECT환인존재주의망락손해,차전간발병년령시영향환인주의망락수평적위험인소.
Objective To investigate the characteristics of attention networks impairment in benign epilepsy children with centrotemporal spikes.Methods The attention network test was performed in benign epilepsy children with centrotemporal spikes (n =75) and normal controls (n =75) on the efficiency of three anatomically defined attention networks:alerting,orienting,and execrtive control.Results The correct rate of attention network test was significantly lower in benign epilepsy children with centrotemporal spikes (95.77％ ± 5.63％) than that in normal controls (98.55％ ± 1.80％ ; t =4.063,P ＜ 0.05).The total average response time was significantly longer in benign epilepsy children with centrotemporal spikes ((946.87 ± 199.82) ms) than that in normal controls ((729.00 ± 146.75) ms ; t =-7.611,P ＜ 0.05).The orienting network effect (29 (12,56)ms) was lower in benign epilepsy children with centrotemporal spikes than in normal controls (51 (21,78) ms; Z =-2.771,P =0.006).The executive control network effect was higher in benign epilepsy children with centrotemporal spikes (80 (50,105) ms) than in normal controls (57 (25,88) ms; Z =-2.146,P =0.032).However,the difference in alerting network effects between the two groups was not statistically significant (P ＞ 0.05).Logistic regression analysis showed that the age on onset of the disease was an independent risk factor for the correct rate of attention network test and the total average response time (OR =1.830,95％ CI 1.193-2.807,P =0.006 ; OR =1.635,95％ CI 1.176-2.275,P =0.003).Conclusions The benign epilepsy children with centrotemporal spikes have impairment of attention networks.The age on onset of the disease has a significant impact on the attention of children with rolandic epilepsy.
