CAJ | 학술논문

胶质母细胞瘤是最常见的颅内原发恶性肿瘤，主要是由星形胶质细胞分化的恶性程度最高的肿瘤。胶质母细胞瘤患者的治疗复杂、致残率高、生存率低、平均生存期短等都是临床工作中遇到的困难，而患者的预后及生存率与诸多因素相关。MRI对于临床制定GBM治疗方案提供了客观依据，对于术前最初形态的分析测量，以及肿瘤对治疗敏感度的监测和分析得到了各界学者的肯定。MRI在预测胶质母细胞瘤患者预后方面，可利用不同的MRI序列通过肿瘤患者的肿瘤范围、水肿坏死程度等指标评估患者肿瘤因素并结合临床综合对患者的生存期做出预测，并对患者治疗后的情况做出预测。
효질모세포류시최상견적로내원발악성종류，주요시유성형효질세포분화적악성정도최고적종류。효질모세포류환자적치료복잡、치잔솔고、생존솔저、평균생존기단등도시림상공작중우도적곤난，이환자적예후급생존솔여제다인소상관。MRI대우림상제정GBM치료방안제공료객관의거，대우술전최초형태적분석측량，이급종류대치료민감도적감측화분석득도료각계학자적긍정。MRI재예측효질모세포류환자예후방면，가이용불동적MRI서렬통과종류환자적종류범위、수종배사정도등지표평고환자종류인소병결합림상종합대환자적생존기주출예측，병대환자치료후적정황주출예측。
Glioblastoma multiforme (GBM) is the most common form of primary brain cancer and the most malignant neoplasm with predominant astroytic differentiation. The patient with GBM has met the dififculty of complicated treatment, high morbidity and mortality, and short mean lifetime after surgery during the clinic work. There are many inlfuencing factors related to the prognosis. Magnetic resonance imaging (MRI) provides information to assist clinicians in making important decisions of treatment plan, and has been respected in the matter of morphologic analysis before the surgery, supervision and analysis of the effect of treatment. It is considered that MRI can do some prediction of the patients with GBM by using different sequence of MRI with index like scoup of the tumor, necrosis and edema.