中国糖尿病杂志
中國糖尿病雜誌
중국당뇨병잡지
CHINESE JOURNAL OF DIABETES
2015年
5期
438-440
,共3页
中性粒细胞/淋巴细胞比值%糖尿病视网膜病变%糖尿病 ,2型
中性粒細胞/淋巴細胞比值%糖尿病視網膜病變%糖尿病 ,2型
중성립세포/림파세포비치%당뇨병시망막병변%당뇨병 ,2형
Neutrophil-to-lymphocyte ratio (NLR)%Diabetic retinopathy (DR)%Diabetes mellitus,type 2
目的：探讨T2DM患者血清中性粒细胞／淋巴细胞比值（NLR）与DR的相关性。方法将128例T2DM患者分为增殖型DR（PDR）者22例、非增殖型DR（NPDR）者44例和单纯 T2DM 者62例。检测各组FPG、HbA1 c、TC、TG和 NLR等指标水平。结果 Spearman相关性分析显示，DR与T2DM 病程、SBP、DBP、FPG、HbA1c、TC、TG、LDL‐C、NLR、CKD呈正相关（r＝0.524、0.277、0.279、0.194、0.271、0.208、0.223、0.358、0.621、0.362，P＜0.05或 P＜0.01）。Logistic多元回归分析结果显示，T2DM病程、NLR和糖尿病慢性肾脏疾病（CKD）是DR的独立影响因素。结论 NLR与DR存在相关性。
目的：探討T2DM患者血清中性粒細胞／淋巴細胞比值（NLR）與DR的相關性。方法將128例T2DM患者分為增殖型DR（PDR）者22例、非增殖型DR（NPDR）者44例和單純 T2DM 者62例。檢測各組FPG、HbA1 c、TC、TG和 NLR等指標水平。結果 Spearman相關性分析顯示，DR與T2DM 病程、SBP、DBP、FPG、HbA1c、TC、TG、LDL‐C、NLR、CKD呈正相關（r＝0.524、0.277、0.279、0.194、0.271、0.208、0.223、0.358、0.621、0.362，P＜0.05或 P＜0.01）。Logistic多元迴歸分析結果顯示，T2DM病程、NLR和糖尿病慢性腎髒疾病（CKD）是DR的獨立影響因素。結論 NLR與DR存在相關性。
목적：탐토T2DM환자혈청중성립세포／림파세포비치（NLR）여DR적상관성。방법장128례T2DM환자분위증식형DR（PDR）자22례、비증식형DR（NPDR）자44례화단순 T2DM 자62례。검측각조FPG、HbA1 c、TC、TG화 NLR등지표수평。결과 Spearman상관성분석현시，DR여T2DM 병정、SBP、DBP、FPG、HbA1c、TC、TG、LDL‐C、NLR、CKD정정상관（r＝0.524、0.277、0.279、0.194、0.271、0.208、0.223、0.358、0.621、0.362，P＜0.05혹 P＜0.01）。Logistic다원회귀분석결과현시，T2DM병정、NLR화당뇨병만성신장질병（CKD）시DR적독립영향인소。결론 NLR여DR존재상관성。
Objective To explore the association between serum neutrophil‐to‐lymphocyte ratio (NLR) and DR in T2DM patients . Methods A total of 128 T2DM patients were recruited and divided into three groups :PDR group (n=22) ,NPDR group(n= 44) ,and simple T2DM group(n=62) .The levels of FPG ,HbA1 c ,TC ,TG and NLR were measured in each group . Results Spearman correlation analysis revealed that DR was positively correlated with T 2DM duration ,SBP ,DBP ,FPG ,HbA1 c ,TC , TG ,LDL‐C ,NLR ,CKD (r= 0.524 ,0.277 ,0.279 ,0.194 ,0.271 ,0.208 ,0.223 ,0.358 ,0.621 , 0.362 ,P<0 .05 or P<0 .01) .Logistic multiple regression analysis showed that ,T2DM duration ,NLR and CKD were independent risk factors for DR . Conclusion NLR level is associated with DR .
