实用医学杂志
實用醫學雜誌
실용의학잡지
THE JOURNAL OF PRACTICAL MEDICINE
2015年
9期
1438-1440
,共3页
李靖华%林晓东%陈晓意%粟海霞%吴泽宇
李靖華%林曉東%陳曉意%粟海霞%吳澤宇
리정화%림효동%진효의%속해하%오택우
腹主动脉瘤%动脉粥样硬化%血脂异常%同型半胱氨酸
腹主動脈瘤%動脈粥樣硬化%血脂異常%同型半胱氨痠
복주동맥류%동맥죽양경화%혈지이상%동형반광안산
Abdominal aortic aneurysm%Atherosclerosis%Dyslipidemia%Homocysteine
目的:为早期筛查腹主动脉瘤(abdominal aortic aneurysm,AAA)以及深入研究动脉粥样硬化在AAA发病中的作用提供理论依据。方法:对广东省人民医院2013-2014年期间30例诊断明确的AAA (病例组)与26例健康人群(对照组)做对照研究,用贝克曼AU5800和贝克曼DXC800检测两组总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、脂蛋白 a(Lpa)、游离脂肪酸(NEFA)、载脂蛋白A(ApoA)、载脂蛋白B(ApoB)以及同型半胱氨酸(HCY)等指标。检测结果采用SPSS 17.0进行两独立样本均数的 t 检验分析。结果:病例组血清 TG 浓度为(1.59±0.56)mmol/L,明显高于对照组的(1.11±0.34)mmol/L(P <0.05)。病例组ApoA和HDL水平分别为(1.08±0.30)g/L和(0.95±0.30)mmol/L,明显低于对照组的(1.41±0.08)g/L和(1.35±0.10)mmol/L (P <0.05)。病例组血清HCY 浓度为(21.00±6.64)μmol/L,明显高于对照组的(10.61±1.99)μmol/L(P <0.05)。两组ApoB、TC、LDL、Lpa、NEFA之间差异无统计学意义(P >0.05)。结论:AAA患者血清TG和HCY水平与其发病呈正相关,ApoA和HDL水平则与其发病呈负相关。
目的:為早期篩查腹主動脈瘤(abdominal aortic aneurysm,AAA)以及深入研究動脈粥樣硬化在AAA髮病中的作用提供理論依據。方法:對廣東省人民醫院2013-2014年期間30例診斷明確的AAA (病例組)與26例健康人群(對照組)做對照研究,用貝剋曼AU5800和貝剋曼DXC800檢測兩組總膽固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、脂蛋白 a(Lpa)、遊離脂肪痠(NEFA)、載脂蛋白A(ApoA)、載脂蛋白B(ApoB)以及同型半胱氨痠(HCY)等指標。檢測結果採用SPSS 17.0進行兩獨立樣本均數的 t 檢驗分析。結果:病例組血清 TG 濃度為(1.59±0.56)mmol/L,明顯高于對照組的(1.11±0.34)mmol/L(P <0.05)。病例組ApoA和HDL水平分彆為(1.08±0.30)g/L和(0.95±0.30)mmol/L,明顯低于對照組的(1.41±0.08)g/L和(1.35±0.10)mmol/L (P <0.05)。病例組血清HCY 濃度為(21.00±6.64)μmol/L,明顯高于對照組的(10.61±1.99)μmol/L(P <0.05)。兩組ApoB、TC、LDL、Lpa、NEFA之間差異無統計學意義(P >0.05)。結論:AAA患者血清TG和HCY水平與其髮病呈正相關,ApoA和HDL水平則與其髮病呈負相關。
목적:위조기사사복주동맥류(abdominal aortic aneurysm,AAA)이급심입연구동맥죽양경화재AAA발병중적작용제공이론의거。방법:대광동성인민의원2013-2014년기간30례진단명학적AAA (병례조)여26례건강인군(대조조)주대조연구,용패극만AU5800화패극만DXC800검측량조총담고순(TC)、감유삼지(TG)、고밀도지단백(HDL)、저밀도지단백(LDL)、지단백 a(Lpa)、유리지방산(NEFA)、재지단백A(ApoA)、재지단백B(ApoB)이급동형반광안산(HCY)등지표。검측결과채용SPSS 17.0진행량독립양본균수적 t 검험분석。결과:병례조혈청 TG 농도위(1.59±0.56)mmol/L,명현고우대조조적(1.11±0.34)mmol/L(P <0.05)。병례조ApoA화HDL수평분별위(1.08±0.30)g/L화(0.95±0.30)mmol/L,명현저우대조조적(1.41±0.08)g/L화(1.35±0.10)mmol/L (P <0.05)。병례조혈청HCY 농도위(21.00±6.64)μmol/L,명현고우대조조적(10.61±1.99)μmol/L(P <0.05)。량조ApoB、TC、LDL、Lpa、NEFA지간차이무통계학의의(P >0.05)。결론:AAA환자혈청TG화HCY수평여기발병정정상관,ApoA화HDL수평칙여기발병정부상관。
Objective To evaluate the relationship between dyslipidemia and abdominal aortic aneurysm (AAA), with which as a theory base and proof we may further study about the mechanism of atherosclerosis (AS) leading to AAA. Methods Thirty abdominal aortic aneurysm patients in Guangdong General Hospital from 2013 to 2014 were enrolled into the experimental group and 26 healthy people into the control group. The serum levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), lipoprotein a (Lpa), nonestesterified fatty acid (NEFA), homocysteine (HCY), apolipoprotein A (ApoA) and apolipoprotein B(ApoB)were tested in the study. The statistical significance of the difference of them was examined by the independent two-sample t-test. Result The serum TG and HCY level in the experimental group were significantly higher than those in the control group (P<0.05). The serum ApoA and HDL level in the experimental group were significantly lower than those in the control group (P<0.05). The serum levels of TC, LDL, Lpa, NEFA and Apo B had no significant difference in both groups (P > 0.05). Conclusion The serum levels of TG and HCY are increased and the levels of Apo A and HDL are decreased in patients with AAA.