CAJ | 학술논문

目的：探讨子宫肌瘤不同术式对内分泌的影响。方法选取2012年1月～2014年12月我院收治的50例子宫肌瘤患者，并根据术式的不同分为甲、乙、丙三组。甲组17例患者行保留附件子宫全切术，乙组17例患者行保留附件子宫次全切除术，丙组16例行子宫肌瘤剔除术，观察并比较三组患者手术前后黄体生成素（LH）、促卵泡激素（FSH）、雌二醇（E2）的变化。结果手术后甲、乙、丙三组都表现为：LH及FSH水平升高和E2水平下降，但是丙组（子宫肌瘤剔除术组）手术前后LH、FSH、E2水平前后比较差异不显著，P>0.05，另外两组这三项指标在术后3个月与术前相比差异显著，P<0.05，在术后6个月与术前相比差异不显著，P>0.05。结论子宫肌瘤不同术式对内分泌都会有一定的影响，但是影响最小的是子宫肌瘤剔除术，在为患者选择手术方式时要根据患者的实际情况，力求在确保肿瘤有效切除的情况下，保留患者的内分泌功能，保证患者的术后生活质量。
목적：탐토자궁기류불동술식대내분비적영향。방법선취2012년1월～2014년12월아원수치적50례자궁기류환자，병근거술식적불동분위갑、을、병삼조。갑조17례환자행보류부건자궁전절술，을조17례환자행보류부건자궁차전절제술，병조16례행자궁기류척제술，관찰병비교삼조환자수술전후황체생성소（LH）、촉란포격소（FSH）、자이순（E2）적변화。결과수술후갑、을、병삼조도표현위：LH급FSH수평승고화E2수평하강，단시병조（자궁기류척제술조）수술전후LH、FSH、E2수평전후비교차이불현저，P>0.05，령외량조저삼항지표재술후3개월여술전상비차이현저，P<0.05，재술후6개월여술전상비차이불현저，P>0.05。결론자궁기류불동술식대내분비도회유일정적영향，단시영향최소적시자궁기류척제술，재위환자선택수술방식시요근거환자적실제정황，력구재학보종류유효절제적정황하，보류환자적내분비공능，보증환자적술후생활질량。
Objective To explore the influence of different hysteromyoma surgical types on endocrine secretion. Methods Fifty patients with hysteromyoma treated in our hospital from January 2012 to December 2014 were selected for this research,and they were divided into three groups,namely,Group A,B and C,seventeen patients in group A were treated with hysterectomy with adnexa uteri not removed,seventeen patients in group B were treated with subtotal hysterectomy with adnexa uteri not removed,sixteen patients in group C were treated with hysteromyomectomy. LH(luteinizing hormone),FSH(fol icle-stimulating hormone)and E2(estradiol)in patients of these groups were observed and compared before and after surgery. Results For patients in groups A,B and C,the level of LH and FSH rose and the level of E2 fel . There was no significant change in the levels of LH,FSH and E2 in patients in Group C(treated with hysteromyomectomy),with P>0.05,while the changes of those levels before surgery and three months thereafter were significant in patients in the other two groups,with P<0.05,and those changes were not significant between those before surgery and six months thereafter,with P>0.05. Conclusion Different operation types for hysteromyoma al have certain influence on endocrine secretion,and hysteromyomectomy has the least impact. It is better to decide which surgical type to take according to patient’s individual situations, and strive to retain patient’s endocrine functions and ensure their post-surgery living quality.