中国卫生标准管理
中國衛生標準管理
중국위생표준관리
CHINA HEALTH STANDARD MANAGEMENT
2015年
11期
167-170
,共4页
变应性鼻炎%免疫治疗%舌下%粉尘螨
變應性鼻炎%免疫治療%舌下%粉塵螨
변응성비염%면역치료%설하%분진만
Al ergic rhinitis sensitized%Immunotherapy%Sublingual%Dust mite
目的：观察并比较标准化粉尘螨滴剂舌下免疫治疗在成人和儿童变应性鼻炎的短期疗效。方法将52例变应性鼻炎患者按年龄分为成人组和儿童组，用标准化粉尘螨滴剂舌下免疫治疗半年，应用记分法和视觉模拟量表（visual analogue scale，VAS）进行鼻部症状评分，分别比较成人组和儿童组治疗半年后鼻部症状评分的变化，并对这两组患者的疗效作一比较。应用SPSS 13.0软件对数据进行统计学分析。结果免疫治疗半年后，成人组和儿童组患者的喷嚏、流涕、鼻塞、鼻痒各症状评分以及鼻部症状总评分（含记分法和VAS法）均下降，差异有统计学意义（P<0.05）。对两组患者免疫治疗前后鼻部症状VAS评分的差值进行比较，结果显示：成人组患者鼻痒VAS评分的下降较儿童组更为显著，组间比较有统计学意义（P=0.003），其他鼻部各症状评分及鼻部整体症状改善程度相似，差异无统计学意义（P>0.05）。结论标准化粉尘螨滴剂舌下免疫治疗对于成人和儿童变应性鼻炎均有疗效,成人组对鼻痒症状的改善尤为显著。
目的：觀察併比較標準化粉塵螨滴劑舌下免疫治療在成人和兒童變應性鼻炎的短期療效。方法將52例變應性鼻炎患者按年齡分為成人組和兒童組，用標準化粉塵螨滴劑舌下免疫治療半年，應用記分法和視覺模擬量錶（visual analogue scale，VAS）進行鼻部癥狀評分，分彆比較成人組和兒童組治療半年後鼻部癥狀評分的變化，併對這兩組患者的療效作一比較。應用SPSS 13.0軟件對數據進行統計學分析。結果免疫治療半年後，成人組和兒童組患者的噴嚏、流涕、鼻塞、鼻癢各癥狀評分以及鼻部癥狀總評分（含記分法和VAS法）均下降，差異有統計學意義（P<0.05）。對兩組患者免疫治療前後鼻部癥狀VAS評分的差值進行比較，結果顯示：成人組患者鼻癢VAS評分的下降較兒童組更為顯著，組間比較有統計學意義（P=0.003），其他鼻部各癥狀評分及鼻部整體癥狀改善程度相似，差異無統計學意義（P>0.05）。結論標準化粉塵螨滴劑舌下免疫治療對于成人和兒童變應性鼻炎均有療效,成人組對鼻癢癥狀的改善尤為顯著。
목적：관찰병비교표준화분진만적제설하면역치료재성인화인동변응성비염적단기료효。방법장52례변응성비염환자안년령분위성인조화인동조，용표준화분진만적제설하면역치료반년，응용기분법화시각모의량표（visual analogue scale，VAS）진행비부증상평분，분별비교성인조화인동조치료반년후비부증상평분적변화，병대저량조환자적료효작일비교。응용SPSS 13.0연건대수거진행통계학분석。결과면역치료반년후，성인조화인동조환자적분체、류체、비새、비양각증상평분이급비부증상총평분（함기분법화VAS법）균하강，차이유통계학의의（P<0.05）。대량조환자면역치료전후비부증상VAS평분적차치진행비교，결과현시：성인조환자비양VAS평분적하강교인동조경위현저，조간비교유통계학의의（P=0.003），기타비부각증상평분급비부정체증상개선정도상사，차이무통계학의의（P>0.05）。결론표준화분진만적제설하면역치료대우성인화인동변응성비염균유료효,성인조대비양증상적개선우위현저。
Objective To observe and compare the short-term efficacy of sublingual immunotherapy(SLIT)with dust mite between adult and children patients with al ergic rhinitis. Methods Separate fifty-two patients with al ergic rhinitis into children group and adult group according to their age,and treated with sublingual immunotherapy with dust mite for half a year,score the nasal symptom by using 4-point rating scale and visual analogue scale(VAS), compare the 2 patient groups’score difference before and after half a year’s treatment,and compared the efficacy of that 2 groups of patients. software SPSS 13.0 were used. Results Both adult and children groups significantly reduced the individual symptom score of sneezing,rhinorrhea,nasal obstruction and pruritus,and the total nasal symptom scores(including 4-point rating scale and VAS)after half a year treatment when compared with the baseline(P<0.05),however,a significant reduction of VAS score of pruritus was found in adult group after half a year treatment,compared with children group(P=0.003). There was no significant difference in decreased VAS score of three other nasal symptoms as wel as the overal improvement of nasal symptoms between two groups of patients(P>0.05). Conclusion There is significant efficacy for child and adult patients with al ergic rhinitis who treated by sublingual immunotherapy(SLIT)with dust mite,especial y for the adult patient with pruritus symptom.
