CAJ | 학술논문

目的：系统综述中医药治疗对缺血性中风患者远期活动能力的影响；方法运用Co-chrane系统综述方法收集国内外发表的中医药治疗缺血性中风的随机对照试验( randomized con-trolled trial,RCT),评价中医药治疗对缺血性中风患者远期活动能力的影响。结果共检索到文献9180篇,最终纳入24项RCT,研究提示中医药治疗可以提高患者远期活动能力( mRS、BI评分),中医药治疗组远期结局良好和相对独立患者比例高于对照组,差异具有统计学意义。结论中医药可以提高缺血性中风患者的远期活动能力,降低患者的死亡人数和复发率,尚需进一步完善试验设计,关注远期疗效,为中医药治疗缺血性中风提供更高级别的循证依据。
목적：계통종술중의약치료대결혈성중풍환자원기활동능력적영향；방법운용Co-chrane계통종술방법수집국내외발표적중의약치료결혈성중풍적수궤대조시험( randomized con-trolled trial,RCT),평개중의약치료대결혈성중풍환자원기활동능력적영향。결과공검색도문헌9180편,최종납입24항RCT,연구제시중의약치료가이제고환자원기활동능력( mRS、BI평분),중의약치료조원기결국량호화상대독립환자비례고우대조조,차이구유통계학의의。결론중의약가이제고결혈성중풍환자적원기활동능력,강저환자적사망인수화복발솔,상수진일보완선시험설계,관주원기료효,위중의약치료결혈성중풍제공경고급별적순증의거。
Objective To systematically evaluate the efficacy of Chinese Medicine( TCM) on the long-term activities after ischemic stroke. Methods By means of Cochrane systematic review, randomized controlled trials( RCTs) on TCM treating acute ischemic stroke were collected. The Modified Rankin Scale (mRS) and Bathel-Index (BI) were used to evaluate the long-term activities of daily life after ischemic stroke. Rates of recurrence and mortality in the trials were also observed. Results 9180 publications were searched and a total of 24 RCTs were included finally. According to the Meta analysis, significantly lower mRS score and higher BI score were seen in the TCM group compared to that of in the control group and western medicine group. Conclusion Improvement of the long-term activities of daily life might be got through the treatment of TCM, which also may reduce the mortality rate and the incidence of secondary stroke. Furthermore, to reveal the advantages of TCM in treating ischemic stroke,we should improve the design of RCTs and pay more attention to the long-term follow-up results.