糖尿病新世界
糖尿病新世界
당뇨병신세계
DIABETES NEW WORLD
2015年
4期
4-5
,共2页
糖尿病%尿路感染%病原菌
糖尿病%尿路感染%病原菌
당뇨병%뇨로감염%병원균
Diabetes%Urinary tract infection%Pathogen
目的：探讨糖尿病合并尿路感染的病原菌分布及其对抗菌药物的耐药情况，为临床合理应用抗生素提供指导。方法对2011年6月—2014年6月间在该院住院的69例糖尿病合并尿路感染患者的临床资料进行回顾性分析。结果在69例糖尿病合并尿路感染患者中段尿标本中共检出92株病原菌，其中革兰阴性杆菌60株，占65.21%；革兰阳性菌25株，占27.17%；真菌7株，占7.61%。革兰阴性杆菌对亚胺培南高度敏感，革兰阳性菌中肠球菌对哌拉西林/他唑巴坦、万古霉素的耐药率较低，对其他抗菌药物的耐药率达40%~77%，金黄色葡萄球菌对万古霉素高度敏感，对青霉素耐药率达90%，对红霉素耐药率达85.5%。结论糖尿病合并尿路感染病原菌以革兰阴性杆菌为主，其次为革兰阳性球菌和真菌，对常用抗菌药物的耐药率较高，普遍存在多重耐药现象，开展病原菌及耐药性监测对于提高糖尿病合并尿路感染的诊治水平具有积极意义。
目的：探討糖尿病閤併尿路感染的病原菌分佈及其對抗菌藥物的耐藥情況，為臨床閤理應用抗生素提供指導。方法對2011年6月—2014年6月間在該院住院的69例糖尿病閤併尿路感染患者的臨床資料進行迴顧性分析。結果在69例糖尿病閤併尿路感染患者中段尿標本中共檢齣92株病原菌，其中革蘭陰性桿菌60株，佔65.21%；革蘭暘性菌25株，佔27.17%；真菌7株，佔7.61%。革蘭陰性桿菌對亞胺培南高度敏感，革蘭暘性菌中腸毬菌對哌拉西林/他唑巴坦、萬古黴素的耐藥率較低，對其他抗菌藥物的耐藥率達40%~77%，金黃色葡萄毬菌對萬古黴素高度敏感，對青黴素耐藥率達90%，對紅黴素耐藥率達85.5%。結論糖尿病閤併尿路感染病原菌以革蘭陰性桿菌為主，其次為革蘭暘性毬菌和真菌，對常用抗菌藥物的耐藥率較高，普遍存在多重耐藥現象，開展病原菌及耐藥性鑑測對于提高糖尿病閤併尿路感染的診治水平具有積極意義。
목적：탐토당뇨병합병뇨로감염적병원균분포급기대항균약물적내약정황，위림상합리응용항생소제공지도。방법대2011년6월—2014년6월간재해원주원적69례당뇨병합병뇨로감염환자적림상자료진행회고성분석。결과재69례당뇨병합병뇨로감염환자중단뇨표본중공검출92주병원균，기중혁란음성간균60주，점65.21%；혁란양성균25주，점27.17%；진균7주，점7.61%。혁란음성간균대아알배남고도민감，혁란양성균중장구균대고랍서림/타서파탄、만고매소적내약솔교저，대기타항균약물적내약솔체40%~77%，금황색포도구균대만고매소고도민감，대청매소내약솔체90%，대홍매소내약솔체85.5%。결론당뇨병합병뇨로감염병원균이혁란음성간균위주，기차위혁란양성구균화진균，대상용항균약물적내약솔교고，보편존재다중내약현상，개전병원균급내약성감측대우제고당뇨병합병뇨로감염적진치수평구유적겁의의。
Objective To investigate the pathogen distribution and antimicrobial resistance in diabetes complicated by urinary tract infection so as to provide guidance for clinical rational use of antibiotics. Methods A retrospective analysis was conducted on 69 cases with diabetes and urinary tract infection hospitalized in our hospital from June 2011 to June 2014. Results A total of 92 strains of pathogenic bacteria were detected from the midstream specimens of urine of 69 cases with diabetes and urinary tract in-fection, of which, there were 60 strains of gram-negative bacilli, accounting for 65.21%; 25 strains of gram-positive bacteria, ac-counting for 27.17%; 7 strains of fungi, accounting for 7.61%. Gram-negative bacilli were highly sensitive to imipenem. Gram-positive bacteria had low rate of drug resistance to piperacillin/tazobactam and vancomycin, but had high rate of drug resistance to other antibacterial drugs, which reached 40%~77%. Staphylococcus aureus was highly sensitive to vancomycin, its rate of drug re-sistance to penicillin reached 90%, to erythromycin reached 85.5%. Conclusion The pathogens of diabetes complicated by urinary tract infection are mainly gram-negative bacilli, followed by gram-positive cocci and fungi, and they have high rate of resistance to common antimicrobials and prevalence of multidrug resistance generally. Thus, carrying out the monitoring of pathogens and drug resistance is of positive significance in improving the level of diagnosis and treatment of diabetes complicated by urinary tract in-fection.
