CAJ | 학술논문

目的：探讨舌下特异性免疫疗法治疗儿童特应性皮炎的临床疗效。方法选择170例儿童特应性皮炎患儿为研究对象，采用随机数字表法分为治疗组和对照组各85例。对照组采用常规抗过敏治疗，治疗组给予舌下特异性免疫疗法。观察两组患儿临床症状改善情况及治疗效果。结果治疗组总有效率明显高于对照组（94．12％vs 76．47％），皮损面积、皮损严重程度、瘙痒感明显低于对照组（1．11±0．38 vs 1．46±0．54，2．03±0．54 vs 3．01±0．78，0．88±0．05 vs 1．09±0．28）。结论舌下特异性免疫疗法有助于改善儿童特应性皮炎临床症状，提高治疗效果。
목적：탐토설하특이성면역요법치료인동특응성피염적림상료효。방법선택170례인동특응성피염환인위연구대상，채용수궤수자표법분위치료조화대조조각85례。대조조채용상규항과민치료，치료조급여설하특이성면역요법。관찰량조환인림상증상개선정황급치료효과。결과치료조총유효솔명현고우대조조（94．12％vs 76．47％），피손면적、피손엄중정도、소양감명현저우대조조（1．11±0．38 vs 1．46±0．54，2．03±0．54 vs 3．01±0．78，0．88±0．05 vs 1．09±0．28）。결론설하특이성면역요법유조우개선인동특응성피염림상증상，제고치료효과。
Objective To investigate the clinical effect of specific immune therapy under the tongue in the treatment of children with atopic dermatitis.Methods 170 children with atopic dermatitis were as the research objects, were randomly divided into treatment group and control group,85 cases in each group.Patients in the control group received conventional anti allergy treatment, patients in the treatment group received sublingual specific immune therapy.The improvement of clinical symptoms and treatment effect were observed. Results The total effective rate in the treatment group was significantly higher than that in the control group (94.12%vs 76.47%), the lesion area, the severity of lesions, itching obviously lower than that in control group (1.11 ±0.38 vs 1.46 ±0.54, 2.03 ±0.54 vs 3.01 ±0.78, 0.88 ±0.05 vs 1.09 ±0.28).Conclusions Specific sublingual immunotherapy is helpful to improve the clinical symptoms in children with atopic dermatitis, which can improve the treatment effect.