CAJ | 학술논문

目的：应用事件相关电位（ ERPs）技术检测不同单胺氧化酶（ MAO） A多态性被试者的抑制控制特征。方法以36名在校正常大学生为被试，应用连接酶特异检测反应（ LDR）测定被试基因型，采用 Go／Nogo范式，Neuroscan系统记录并分析被试者脑电图，比较不同基因型被试的脑电图特征。结果三组被试的Go／Nogo任务的行为反应无明显差异。三组被试 N2波波幅差异不显著， CT 组被试 Go和 Nogo试次的 P3波幅较CC组和TT组被试均显著增大，N2和P3差异波的差异不显著。结论三组被试抑制控制能力差异不显著，但 CT组被试在加工处理信息过程中动员的认知资源更多，具有不同的脑电图活动特征。
목적：응용사건상관전위（ ERPs）기술검측불동단알양화매（ MAO） A다태성피시자적억제공제특정。방법이36명재교정상대학생위피시，응용련접매특이검측반응（ LDR）측정피시기인형，채용 Go／Nogo범식，Neuroscan계통기록병분석피시자뇌전도，비교불동기인형피시적뇌전도특정。결과삼조피시적Go／Nogo임무적행위반응무명현차이。삼조피시 N2파파폭차이불현저， CT 조피시 Go화 Nogo시차적 P3파폭교CC조화TT조피시균현저증대，N2화P3차이파적차이불현저。결론삼조피시억제공제능력차이불현저，단 CT조피시재가공처리신식과정중동원적인지자원경다，구유불동적뇌전도활동특정。
Objective To explore the effect of MAO A polymorphism on the inhibitory control by ERPs.Methods A total of 36 health of college students were investigated.The amplitudes and latencies of ERP components were studied with a visual Go/Nogo task,and the MAO A polymorphism of the participants was tested by LDR.Results The behavioral data were not different.The amplitudes and laten-cies of N2 component were not different in the three groups.The amplitudes of P3 component of CT group were higher than those of the other two groups.No differences of N2 and P3 waves were found.Conclusions The more cognitive resources are mobilized in CT group than those of the other two groups.