CAJ | 학술논문

目的：探讨液相色谱-串联质谱法(LC-MS/MS)测定鳗鱼中甲苯咪唑含量的不确定度评价方法。方法根据JJF1059.1-2012《测量不确定度的评定与表示》,参考《化学分析中不确定度的评定的评估指南》及《实用测量不确定度评定》等相关理论,对测定过程中甲苯咪唑含量、样品定容体积、样品称量质量、称量样品稀释、样品重复性等引入的不确定度分量进行评定,评定鳗鱼中甲苯咪唑残留量测定的不确定度。结果测定结果合成不确定度为1.6×10-4 mg/kg,扩展不确定度为3.2×10-4 mg/kg。结论建立的不确定度评定方法适用于LC-MS/MS法测定鳗鱼中甲苯咪唑残留量的不确定度评定。
목적：탐토액상색보-천련질보법(LC-MS/MS)측정만어중갑분미서함량적불학정도평개방법。방법근거JJF1059.1-2012《측량불학정도적평정여표시》,삼고《화학분석중불학정도적평정적평고지남》급《실용측량불학정도평정》등상관이론,대측정과정중갑분미서함량、양품정용체적、양품칭량질량、칭량양품희석、양품중복성등인입적불학정도분량진행평정,평정만어중갑분미서잔류량측정적불학정도。결과측정결과합성불학정도위1.6×10-4 mg/kg,확전불학정도위3.2×10-4 mg/kg。결론건립적불학정도평정방법괄용우LC-MS/MS법측정만어중갑분미서잔류량적불학정도평정。
Objective To investigate the method that uncertainty evaluation of the determination of mebendazole content in eel by liquid chromatography-mass spectrometry/mass spectrometry (LC/MS/MS). Methods Based on JJF 1059.1-2012 Evaluation and expression of uncertainty in measurement, Guidance on evaluating the uncertainty in chemical analysis and The practical measurement uncertainty evaluation and other related theory, the uncertainty component that content of mebendazole, constant volume, mass, and the diluent and repetition for the sample were evaluated in the process of determination. Then uncertainty measurement of mebendazole residues in eel was evaluated. Results The results showed that the combined uncertainty of mebendazole residues in eel was 1.6×10-4 mg/kg, the expanded uncertainty was 3.2×10-4 mg/kg. Conclusion This uncertainty evaluation method is suitable for determination of mebendazole residues in eel by LC-MS/MS.