血栓与止血学
血栓與止血學
혈전여지혈학
CHINESE JOURNAL OF THROMBOSIS AND HEMOSTASIS
2015年
2期
77-79
,共3页
冠心病%心血管意外%凝血功能
冠心病%心血管意外%凝血功能
관심병%심혈관의외%응혈공능
Coronary heart disease%Cardiovascular accidents%Blood coagulation function
目的:研究冠心病患者心血管意外和凝血功能相关性。方法从2013年4月到2014年1月,选取我院的96例冠心病患者进行回顾性分析,均采用冠脉CT检查心血管凝血情况,分析了解凝血功能与心血管意外的相关性。结果96例冠心病患者进行了随访,其中有16例患者因心血管意外而死亡,其中有34名患者发生心血管意外但并不致死,死亡以及非致死性心血管意外患者的调查中血浆高密度脂蛋白浓度较低,同时C反应蛋白,白细胞介素浓度较高;心血管意外死亡组患者的凝血功能指标显著高于比非致死性心血管意外组,而非致死性心血管意外组又显著高于无心血管意外组,组间的比较差异具有统计学意义(P<0.05);凝血因子水平和其他心血管危险因素的关系vWF、PAP、浓度随着年龄的增长而升高,纤维蛋白原、TAT水平与年龄无关,其他凝血功能参数和心血管影响因素的关系。结论冠心病患者心血管意外与高凝血状态有一定的关系,为了减少心血管意外的发生。
目的:研究冠心病患者心血管意外和凝血功能相關性。方法從2013年4月到2014年1月,選取我院的96例冠心病患者進行迴顧性分析,均採用冠脈CT檢查心血管凝血情況,分析瞭解凝血功能與心血管意外的相關性。結果96例冠心病患者進行瞭隨訪,其中有16例患者因心血管意外而死亡,其中有34名患者髮生心血管意外但併不緻死,死亡以及非緻死性心血管意外患者的調查中血漿高密度脂蛋白濃度較低,同時C反應蛋白,白細胞介素濃度較高;心血管意外死亡組患者的凝血功能指標顯著高于比非緻死性心血管意外組,而非緻死性心血管意外組又顯著高于無心血管意外組,組間的比較差異具有統計學意義(P<0.05);凝血因子水平和其他心血管危險因素的關繫vWF、PAP、濃度隨著年齡的增長而升高,纖維蛋白原、TAT水平與年齡無關,其他凝血功能參數和心血管影響因素的關繫。結論冠心病患者心血管意外與高凝血狀態有一定的關繫,為瞭減少心血管意外的髮生。
목적:연구관심병환자심혈관의외화응혈공능상관성。방법종2013년4월도2014년1월,선취아원적96례관심병환자진행회고성분석,균채용관맥CT검사심혈관응혈정황,분석료해응혈공능여심혈관의외적상관성。결과96례관심병환자진행료수방,기중유16례환자인심혈관의외이사망,기중유34명환자발생심혈관의외단병불치사,사망이급비치사성심혈관의외환자적조사중혈장고밀도지단백농도교저,동시C반응단백,백세포개소농도교고;심혈관의외사망조환자적응혈공능지표현저고우비비치사성심혈관의외조,이비치사성심혈관의외조우현저고우무심혈관의외조,조간적비교차이구유통계학의의(P<0.05);응혈인자수평화기타심혈관위험인소적관계vWF、PAP、농도수착년령적증장이승고,섬유단백원、TAT수평여년령무관,기타응혈공능삼수화심혈관영향인소적관계。결론관심병환자심혈관의외여고응혈상태유일정적관계,위료감소심혈관의외적발생。
Objective To study the correlation analysis of cardiovascular accidents and blood coagula-tion function in patients with coronary heart disease(CHD). Methods From April 2013 to January 2014,se-lected from 96 cases of coronary heart disease patients in our hospital,and they were retrospectively analyzed, both by coronary angiography examination of cardiovascular blood coagulation, analyzed and understood the correlation of blood coagulation function and cardiovascular accident. Results 96 cases of coronary heart dis-ease patients who were followed up,there are 16 patients died when the cardiovascular accident,there were 34 patients with cardiovascular accident but not death,death,nonfatal cardiovascular accident investigation in the patients with plasma high-density lipoprotein cholesterol( hdl-c) concentration was low,at the same time c-re-active protein, interleukin higher levels;Index of blood coagulation function in patients with cardiovascular death group was significantly higher than than nonfatal cardiovascular accident group,and nonfatal cardiovas-cular accident group was significantly higher than that without cardiovascular accident, the comparison of differences between groups with statistical significance(P<0. 05);Clotting factor the relations,and other car-diovascular risk factors vWF,PAP, concentration with increasing age,level of fibrinogen,TAT has nothing to do with age,other blood coagulation function relationship and the influence factor of cardiovascular parame-ters. Conclusion Patients with coronary heart disease, cardiovascular accident have a certain relationship with high coagulation state,in order to reduce the occurrence of cardiovascular accident,need to be timely pre-vention and treatment,and anticoagulant therapy to prevent and correct the high coagulation state is preven-tion,commonly used in the treatment of cardiovascular accident means,is worth further promotion in the clini-cal practice.