CAJ | 학술논문

目的：研究分析尼莫司汀对复发恶性胶质瘤的临床效果。方法：选取2010年1月至2014年1月期间，本院收治的复发恶性胶质瘤患者100例，通过随机数表法将全部患者分为对照组与观察组，各组患者50例，对照组患者采用单纯三维适形放疗，观察组患者在此基础上联合灌注尼莫司汀进行治疗，对比分析两组的治疗效果。结果：经分析可知，观察组总有效率为90.00%；对照组总有效率为68.00%，两组对比有统计学差异（P<0.05）。观察组不良反应患者接受相应的针对治疗之后，缓解恢复，无死亡患者。结论：对复发恶性胶质瘤患者采用尼莫司汀治疗，临床效果显著，不良反应发生率低，安全可靠，可以作为常规的化疗手段，值得在临床上推广使用。
목적：연구분석니막사정대복발악성효질류적림상효과。방법：선취2010년1월지2014년1월기간，본원수치적복발악성효질류환자100례，통과수궤수표법장전부환자분위대조조여관찰조，각조환자50례，대조조환자채용단순삼유괄형방료，관찰조환자재차기출상연합관주니막사정진행치료，대비분석량조적치료효과。결과：경분석가지，관찰조총유효솔위90.00%；대조조총유효솔위68.00%，량조대비유통계학차이（P<0.05）。관찰조불량반응환자접수상응적침대치료지후，완해회복，무사망환자。결론：대복발악성효질류환자채용니막사정치료，림상효과현저，불량반응발생솔저，안전가고，가이작위상규적화료수단，치득재림상상추엄사용。
Objective: clinical observation of nimustine in recurrent malignant glioma. Methods: the patients were divided into control group and observation group, the control group using a simple three-dimensional conformal radiation therapy, the observation group based on the combined perfusion nimustine therapy, compared two groups of treatment effect. Results:the total effective rate of observation group was 90%;the control group the total effective rate was 68%, two groups had significant difference (P<0.05) contrast. Conclusion:the recurrence of malignant glioma patients using the Nimmo Stine treatment, a significant clinical effect, low incidence of adverse reactions, safe and reliable, can be used as a means of conventional chemotherapy, worthy of promotion in clinical use.