糖尿病新世界
糖尿病新世界
당뇨병신세계
DIABETES NEW WORLD
2015年
2期
15-16
,共2页
糖尿病%创口感染%病原菌%药敏分析
糖尿病%創口感染%病原菌%藥敏分析
당뇨병%창구감염%병원균%약민분석
Diabetes%Wound infection%Pathogen%Drug sensitivity analysis
目的：探讨糖尿病患者继发创口感染病原菌的分布及药敏耐药情况，为临床抗感染治疗提供用药依据。方法选取该院2011年1月—2013年12月收治的98例糖尿病继发创口感染患者为研究对象，采集上述患者的受损皮肤、头部或足部等部位的伤口分泌物及脓液等作为创口标本，对其进行细菌培养，分离并鉴定病原菌，分析其病原菌分布及药敏耐药情况。结果98例糖尿病继发创口感染患者共分离培养出病原菌108株。药敏分析结果显示，革兰阳性菌中金黄色葡萄球菌对头孢唑啉、青霉素的耐药率均达100%；凝固酶阴性葡萄球菌对青霉素的耐药率达100%，对头孢唑啉、氨苄西林/舒巴坦的耐药率达93%以上；肠球菌属对四环素、红霉素的耐药率达70%以上，对其它抗菌药物的耐药率较低。革兰阴性杆菌对常用抗菌药物的敏感性较好。结论糖尿病患者创口感染的病原菌以革兰阳性菌为主，应定期开展耐药监测，合理使用抗生素，以提高抗感染治疗效果。
目的：探討糖尿病患者繼髮創口感染病原菌的分佈及藥敏耐藥情況，為臨床抗感染治療提供用藥依據。方法選取該院2011年1月—2013年12月收治的98例糖尿病繼髮創口感染患者為研究對象，採集上述患者的受損皮膚、頭部或足部等部位的傷口分泌物及膿液等作為創口標本，對其進行細菌培養，分離併鑒定病原菌，分析其病原菌分佈及藥敏耐藥情況。結果98例糖尿病繼髮創口感染患者共分離培養齣病原菌108株。藥敏分析結果顯示，革蘭暘性菌中金黃色葡萄毬菌對頭孢唑啉、青黴素的耐藥率均達100%；凝固酶陰性葡萄毬菌對青黴素的耐藥率達100%，對頭孢唑啉、氨芐西林/舒巴坦的耐藥率達93%以上；腸毬菌屬對四環素、紅黴素的耐藥率達70%以上，對其它抗菌藥物的耐藥率較低。革蘭陰性桿菌對常用抗菌藥物的敏感性較好。結論糖尿病患者創口感染的病原菌以革蘭暘性菌為主，應定期開展耐藥鑑測，閤理使用抗生素，以提高抗感染治療效果。
목적：탐토당뇨병환자계발창구감염병원균적분포급약민내약정황，위림상항감염치료제공용약의거。방법선취해원2011년1월—2013년12월수치적98례당뇨병계발창구감염환자위연구대상，채집상술환자적수손피부、두부혹족부등부위적상구분비물급농액등작위창구표본，대기진행세균배양，분리병감정병원균，분석기병원균분포급약민내약정황。결과98례당뇨병계발창구감염환자공분리배양출병원균108주。약민분석결과현시，혁란양성균중금황색포도구균대두포서람、청매소적내약솔균체100%；응고매음성포도구균대청매소적내약솔체100%，대두포서람、안변서림/서파탄적내약솔체93%이상；장구균속대사배소、홍매소적내약솔체70%이상，대기타항균약물적내약솔교저。혁란음성간균대상용항균약물적민감성교호。결론당뇨병환자창구감염적병원균이혁란양성균위주，응정기개전내약감측，합리사용항생소，이제고항감염치료효과。
Objective To investigate the distribution of pathogens and drug sensitivity of secondary wound infection in diabetic pa-tients so as to provide a basis of medication for clinical anti-infection treatment. Methods 98 diabetic patients with secondary wound infection admitted in our hospital from January 2011 to December 2013 were selected as the subjects. The wound secretion and fester in the damaged skin, head or feet or other position were collected as the wound specimens and for bacterial culture. The bacteria were isolated and identified. And the distribution and drug sensitivity and resistance of the bacteria were analyzed. Re-sults A total of 108 pathogens were isolated and cultured from the wound secretion and fester of the 98 diabetic patients with sec-ondary wound infection. The drug sensitivity analysis showed that the drug resistance rate of Staphylococcus aureus in Gram-posi-tive bacteria to cefazolin and penicillin reached 100%; and that of coagulase negative staphylococcus to penicillin reached 100%, to cefazolin, ampicillin/sulbactam reached over 93%; the drug resistance rate of enterococcus to tetracycline and erythromycin reached over 70%, but had lower drug resistance rate to other antimicrobial drugs. Gram-negative bacilli had high sensitivity to commonly used antibiotics. Conclusion The pathogens of wound infection in diabetic patients are mainly Gram-positive bacteria. Regularly carrying out drug resistance surveillance and rationally using the antibiotics can improve the anti-infection treatment ef-fect.
