中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2015年
5期
342-345
,共4页
韩景奇%李涌%陈明%李文华%张传玉
韓景奇%李湧%陳明%李文華%張傳玉
한경기%리용%진명%리문화%장전옥
结直肠肿瘤%肿瘤转移%导管消融术
結直腸腫瘤%腫瘤轉移%導管消融術
결직장종류%종류전이%도관소융술
Colorectal neoplasms%Neoplasm metastasis%Catheter ablation
目的 评价CT引导下射频消融治疗结直肠癌肺内孤立性转移灶的安全性、局部控制效果及生存率.方法 对28例结直肠癌肺内孤立性转移灶患者进行CT引导下射频消融治疗(射频消融组),病灶直径1.2～5.0(2.9±1.0) cm;并将9例未采取任何治疗的结直肠癌肺内孤立性转移灶患者作为对照组,病灶直径2.0～5.0 (3.6± 1.0) cm.比较两组局部无进展率及总生存率.结果 射频消融组患者均能完成射频消融治疗,术中、术后未发生严重并发症.射频消融组1,2和3年局部无进展率和总生存率明显高于对照组(局部无进展率:89.3％比76.2％、78.6％比33.9％、70.7％比16.9％,总生存率:96.4％比77.8％、85.7％比44.4％、56.7％比22.2％),差异有统计学意义(P＜ 0.01).结论 CT引导下射频消融治疗结直肠癌肺内孤立性转移灶微创、安全有效,可明显提高局部无进展率及总生存率.
目的 評價CT引導下射頻消融治療結直腸癌肺內孤立性轉移竈的安全性、跼部控製效果及生存率.方法 對28例結直腸癌肺內孤立性轉移竈患者進行CT引導下射頻消融治療(射頻消融組),病竈直徑1.2～5.0(2.9±1.0) cm;併將9例未採取任何治療的結直腸癌肺內孤立性轉移竈患者作為對照組,病竈直徑2.0～5.0 (3.6± 1.0) cm.比較兩組跼部無進展率及總生存率.結果 射頻消融組患者均能完成射頻消融治療,術中、術後未髮生嚴重併髮癥.射頻消融組1,2和3年跼部無進展率和總生存率明顯高于對照組(跼部無進展率:89.3％比76.2％、78.6％比33.9％、70.7％比16.9％,總生存率:96.4％比77.8％、85.7％比44.4％、56.7％比22.2％),差異有統計學意義(P＜ 0.01).結論 CT引導下射頻消融治療結直腸癌肺內孤立性轉移竈微創、安全有效,可明顯提高跼部無進展率及總生存率.
목적 평개CT인도하사빈소융치료결직장암폐내고립성전이조적안전성、국부공제효과급생존솔.방법 대28례결직장암폐내고립성전이조환자진행CT인도하사빈소융치료(사빈소융조),병조직경1.2～5.0(2.9±1.0) cm;병장9례미채취임하치료적결직장암폐내고립성전이조환자작위대조조,병조직경2.0～5.0 (3.6± 1.0) cm.비교량조국부무진전솔급총생존솔.결과 사빈소융조환자균능완성사빈소융치료,술중、술후미발생엄중병발증.사빈소융조1,2화3년국부무진전솔화총생존솔명현고우대조조(국부무진전솔:89.3％비76.2％、78.6％비33.9％、70.7％비16.9％,총생존솔:96.4％비77.8％、85.7％비44.4％、56.7％비22.2％),차이유통계학의의(P＜ 0.01).결론 CT인도하사빈소융치료결직장암폐내고립성전이조미창、안전유효,가명현제고국부무진전솔급총생존솔.
Objective To evaluate the safety,local efficacy and survival rates of isolated pulmonary metastases from colorectal carcinoma treated with CT-guided radiofrequency ablation.Methods A total of 28 patients with isolated pulmonary metastases from colorectal carcinoma were performed with CT-guided radiofrequency ablation (radiofrequency ablation group).The size of the lesion was 1.2-5.0 (2.9 ± 1.0) cm.During the same time,9 patients,who did not take any treatment for isolated pulmonary metastases from colorectal carcinoma,were collected as control group.The size of the lesion was 2.0-5.0 (3.6 ± 1.0) cm.The local progression-free rates and overall survival rates were compared.Results All the cases were able to complete the radiofrequency ablation in radiofrequency ablation group.During and after the procedure,no major complications occurred.The 1-,2-,and 3-year local progression-free rates and overall survival rates in radiofrequency ablation group were significantly higher than those in control group.The local progression-free rates were 89.3％ vs.76.2％,78.6％ vs.33.9％,70.7％ vs.16.9％.The overall survival rates were 96.4％ vs.77.8％,85.7％ vs.44.4％,56.7％ vs.22.2％.The differences between two groups had statistical significance (P ＜ 0.01).Conclusion CT-guided radiofrequency ablation for isolated pulmonary metastasis from colorectal carcinoma is a safe,effective,minimally invasive treatment,and can significantly improve the local progression-free rates and overall survival rates.
