河北中医
河北中醫
하북중의
HEBEI JORNAL OF TRADITIONAL CHINESE MEDICINE
2015年
5期
660-665
,共6页
程悦蕾%朱惠蓉%张怡%张娟%柴妮
程悅蕾%硃惠蓉%張怡%張娟%柴妮
정열뢰%주혜용%장이%장연%시니
结直肠肿瘤%辨证分型%中医病机%舌质%症候
結直腸腫瘤%辨證分型%中醫病機%舌質%癥候
결직장종류%변증분형%중의병궤%설질%증후
Colorectal neoplasms%Syndrome differentiation%Chinese medical pathogenesis%Tongue nature%Syndrome
目的：探讨湿热蕴结型大肠癌（ CRC）术后患者的舌象变化与中医症候之间的相关性。方法将100例湿热蕴结型CRC术后患者随机分为2组，治疗组72例应用肠益方加减治疗，对照组28例应用平消胶囊治疗。2组均治疗3个月。采用ZBOX－Ⅰ型中医舌脉象数字化采集分析系统采集患者治疗前后的舌象参数，并由计算机软件对舌象参数进行自动分析；同时对患者治疗前后中医症候进行评分；观察治疗前后患者舌象参数与中医症候的变化，并用统计学软件分析舌象参数与中医症候之间的相关性。结果2组治疗前后舌象苔质参数变化比较差异无统计学意义（P＞0．05）。治疗组湿热夹瘀证治疗后胖瘦指数较本组治疗前升高（P＜0．05），胖瘦指数由治疗前的瘦舌转变为治疗后的正常舌；对照组治疗后齿痕指数较本组治疗前降低（P＜0．05）。2组治疗前后中医症候总评分比较差异均有统计学意义（P＜0．05），治疗后降低。治疗组湿热兼虚证治疗后总有效率高于对照组（ P＜0．05）。治疗组治疗后中医单项症候评分均较本组治疗前降低（P＜0．05）；对照组治疗后黏液便、肛门灼热、口苦、神疲乏力、面色萎黄这5项中医症候评分较本组治疗前降低（P＜0．05）。治疗组湿热夹瘀证治疗后面色萎黄这1项中医症候疗效优于对照组（P＜0．05）；治疗组湿热兼虚证治疗后腹部疼痛、腹痛固定、面色萎黄这3项中医症候疗效优于对照组（P＜0．05）。2组患者治疗前后的舌象参数及中医单项症候评分进行Pearson简单相关系数的相关性分析，舌象胖瘦指数与黏液便的相关系数最大为－0．162，且呈负相关（P＜0．05）。结论肠益方能改善湿热夹瘀证CRC术后患者舌象的胖瘦程度；改善湿热蕴结型CRC术后患者的中医症候，且疗效优于对照组；湿热蕴结型CRC术后患者舌象参数与中医症候具有一定的相关性。
目的：探討濕熱蘊結型大腸癌（ CRC）術後患者的舌象變化與中醫癥候之間的相關性。方法將100例濕熱蘊結型CRC術後患者隨機分為2組，治療組72例應用腸益方加減治療，對照組28例應用平消膠囊治療。2組均治療3箇月。採用ZBOX－Ⅰ型中醫舌脈象數字化採集分析繫統採集患者治療前後的舌象參數，併由計算機軟件對舌象參數進行自動分析；同時對患者治療前後中醫癥候進行評分；觀察治療前後患者舌象參數與中醫癥候的變化，併用統計學軟件分析舌象參數與中醫癥候之間的相關性。結果2組治療前後舌象苔質參數變化比較差異無統計學意義（P＞0．05）。治療組濕熱夾瘀證治療後胖瘦指數較本組治療前升高（P＜0．05），胖瘦指數由治療前的瘦舌轉變為治療後的正常舌；對照組治療後齒痕指數較本組治療前降低（P＜0．05）。2組治療前後中醫癥候總評分比較差異均有統計學意義（P＜0．05），治療後降低。治療組濕熱兼虛證治療後總有效率高于對照組（ P＜0．05）。治療組治療後中醫單項癥候評分均較本組治療前降低（P＜0．05）；對照組治療後黏液便、肛門灼熱、口苦、神疲乏力、麵色萎黃這5項中醫癥候評分較本組治療前降低（P＜0．05）。治療組濕熱夾瘀證治療後麵色萎黃這1項中醫癥候療效優于對照組（P＜0．05）；治療組濕熱兼虛證治療後腹部疼痛、腹痛固定、麵色萎黃這3項中醫癥候療效優于對照組（P＜0．05）。2組患者治療前後的舌象參數及中醫單項癥候評分進行Pearson簡單相關繫數的相關性分析，舌象胖瘦指數與黏液便的相關繫數最大為－0．162，且呈負相關（P＜0．05）。結論腸益方能改善濕熱夾瘀證CRC術後患者舌象的胖瘦程度；改善濕熱蘊結型CRC術後患者的中醫癥候，且療效優于對照組；濕熱蘊結型CRC術後患者舌象參數與中醫癥候具有一定的相關性。
목적：탐토습열온결형대장암（ CRC）술후환자적설상변화여중의증후지간적상관성。방법장100례습열온결형CRC술후환자수궤분위2조，치료조72례응용장익방가감치료，대조조28례응용평소효낭치료。2조균치료3개월。채용ZBOX－Ⅰ형중의설맥상수자화채집분석계통채집환자치료전후적설상삼수，병유계산궤연건대설상삼수진행자동분석；동시대환자치료전후중의증후진행평분；관찰치료전후환자설상삼수여중의증후적변화，병용통계학연건분석설상삼수여중의증후지간적상관성。결과2조치료전후설상태질삼수변화비교차이무통계학의의（P＞0．05）。치료조습열협어증치료후반수지수교본조치료전승고（P＜0．05），반수지수유치료전적수설전변위치료후적정상설；대조조치료후치흔지수교본조치료전강저（P＜0．05）。2조치료전후중의증후총평분비교차이균유통계학의의（P＜0．05），치료후강저。치료조습열겸허증치료후총유효솔고우대조조（ P＜0．05）。치료조치료후중의단항증후평분균교본조치료전강저（P＜0．05）；대조조치료후점액편、항문작열、구고、신피핍력、면색위황저5항중의증후평분교본조치료전강저（P＜0．05）。치료조습열협어증치료후면색위황저1항중의증후료효우우대조조（P＜0．05）；치료조습열겸허증치료후복부동통、복통고정、면색위황저3항중의증후료효우우대조조（P＜0．05）。2조환자치료전후적설상삼수급중의단항증후평분진행Pearson간단상관계수적상관성분석，설상반수지수여점액편적상관계수최대위－0．162，차정부상관（P＜0．05）。결론장익방능개선습열협어증CRC술후환자설상적반수정도；개선습열온결형CRC술후환자적중의증후，차료효우우대조조；습열온결형CRC술후환자설상삼수여중의증후구유일정적상관성。
Objective To observe the correlation of tongue parameters in postoperative colorectal cancer pa-tients with damp-heat accumulation type and traditional Chinese medicine ( TCM) syndrome.Methods 100 post-operative colorectal cancer patients with damp -heat accumulation type were randomly divided into two groups .72 pa-tients in treatment group were treated by Changyi herbs ,28 patients in control group were treated by Pingxiao capsule . The course was three months in two groups .The tongue parameters of patients were collected by type ZBOX -I digital collection and analysis system of tongue and pulse manifestation before and after treatment ,and received computer au-tomatic analysis.The scores of TCM syndrome were recorded in two groups .The changes of tongue parameters and TCM syndrome were observed before and after treatment ,and the correlation between tongue parameters and TCM syn-drome were analyzed by statistical software .Results There was no statistical significance between two groups on the tongue parameters before and after treatment ( P <0.05).The fat index of damp -heat accumulation type after treatment was increased in treatment group ( P<0.05),the tongue turn thin tongue before treatment into normal tongue after treatment .The teeth prints after treatment was decreased in control group (P<0.05). There was statistical significance before and after treat-ment on TCM syndrome score in two groups (P<0.05),and the score after treatment was decreased .The total effec-tive rate of damp-heat accumulation type in treatment group was higher than that in control group (P<0.05).The single syndrome score of TCM after treatment were decreased in treatment group (P<0.05).The TCM syndrome score of mucous stool,burning pain in anus,bitter taste,weariness and sallow complexion after treatment were de-creased in control group (P<0.05).The improvements of sallow complexion of damp -heat accumulation type in treatment group after treatment was superior to that in control group (P <0.05).The improvements of abdominal pain,abdominal pain spot fixed and sallow complexion of dampness -heat and deficiency type in treatment group after treatment were superior to those in control group (P<0.05).The correlation of tongue parameters and the single syn-drome score of TCM was analyzed by Pearson simple related coefficient .The maximum correlation coefficient of tongue parameters and mucous stool was -0.162,and a negative correlation (P<0.05).Conclusion Changyi herbs can improve the fatness of tongue in postoperative colorectal cancer patients with damp -heat and stasis type ,improve the TCM syndrome of postoperative colorectal cancer patients with damp -heat accumulation type ,and the effects was su-perior to that in control group .There were some correlation between tongue parameters and TCM syndrome in postoper-ative colorectal cancer patients with damp -heat accumulation type .
