CAJ | 학술논문

炔诺酮等孕激素在临床中单独或以复方形式用于妇科疾病的治疗及避孕。笔者在临床工作中遇到1例因大剂量服用炔诺酮治疗功能性子宫出血而发生眼底病变的病例。本文检索汇总了国外相关文献报道(国内未见报道)，分析了该不良反应可能的发生机制，阐明了临床应用该类药物时的注意事项，以及发生类似不良反应后的处置方案。
결낙동등잉격소재림상중단독혹이복방형식용우부과질병적치료급피잉。필자재림상공작중우도1례인대제량복용결낙동치료공능성자궁출혈이발생안저병변적병례。본문검색회총료국외상관문헌보도(국내미견보도)，분석료해불량반응가능적발생궤제，천명료림상응용해류약물시적주의사항，이급발생유사불량반응후적처치방안。
Norethisterone and other progesterone are commonly presribedfor gynecological diseases or contraception. In this case,patientsuffered retinal pathological change caused by high-dose of norethisterone, which was administered to treat dysfunctional uterine bleeding. We retrieved relative literatures, analyzed the ADR's mechanisms, and provided treatment option. Medical staff should pay more attention to drug contraindications and relative adverse reactions when progesterone was applied to patients.