药品评价
藥品評價
약품평개
DRUG REEVALUATION
2015年
6期
24-34
,共11页
达立通颗粒%莫沙必利%功能性消化不良%成本-效果分析
達立通顆粒%莫沙必利%功能性消化不良%成本-效果分析
체립통과립%막사필리%공능성소화불량%성본-효과분석
Dalitong Granule%Mosapride%Functional Dyspepsia%Cost-effectiveness Analysis
目的：通过对达立通颗粒现有文献的梳理，全面掌握当前达立通颗粒研究文献现状，在此基础上对达立通颗粒与莫沙必利治疗功能性消化不良的成本-效果进行分析。方法：采用meta分析方法，系统的评估达立通颗粒治疗功能性消化不良的效果，采用成本-效果分析方法评价达立通颗粒与莫沙必利治疗功能性消化不良的经济性。结果：达立通颗粒组治疗功能性消化不良的显效率和总有效率略高于莫沙必利组，达立通颗粒安全性良好，不良事件发生率低于莫沙必利组；在为期4周的治疗期间，达立通颗粒组与莫沙必利组相比，效果较好，但成本略高。结论：达立通颗粒与莫沙必利相比，治疗功能性消化不良具有较好的效果优势，影响其增量成本效果比的主要因素是价格。
目的：通過對達立通顆粒現有文獻的梳理，全麵掌握噹前達立通顆粒研究文獻現狀，在此基礎上對達立通顆粒與莫沙必利治療功能性消化不良的成本-效果進行分析。方法：採用meta分析方法，繫統的評估達立通顆粒治療功能性消化不良的效果，採用成本-效果分析方法評價達立通顆粒與莫沙必利治療功能性消化不良的經濟性。結果：達立通顆粒組治療功能性消化不良的顯效率和總有效率略高于莫沙必利組，達立通顆粒安全性良好，不良事件髮生率低于莫沙必利組；在為期4週的治療期間，達立通顆粒組與莫沙必利組相比，效果較好，但成本略高。結論：達立通顆粒與莫沙必利相比，治療功能性消化不良具有較好的效果優勢，影響其增量成本效果比的主要因素是價格。
목적：통과대체립통과립현유문헌적소리，전면장악당전체립통과립연구문헌현상，재차기출상대체립통과립여막사필리치료공능성소화불량적성본-효과진행분석。방법：채용meta분석방법，계통적평고체립통과립치료공능성소화불량적효과，채용성본-효과분석방법평개체립통과립여막사필리치료공능성소화불량적경제성。결과：체립통과립조치료공능성소화불량적현효솔화총유효솔략고우막사필리조，체립통과립안전성량호，불량사건발생솔저우막사필리조；재위기4주적치료기간，체립통과립조여막사필리조상비，효과교호，단성본략고。결론：체립통과립여막사필리상비，치료공능성소화불량구유교호적효과우세，영향기증량성본효과비적주요인소시개격。
Objective: A comprehensive understanding of the current situation of Dalitong granule research was achievedby literature retrieving.Cost-effectiveness analysiswas performed thereafter on Dalitong granule and mosapride in treating functional dyspepsia.Method: The effectiveness of Dalitong granule in the treatment of functional dyspepsia was evulated with meta analysis. The economic benefit of Dalitong granule and mosapride in treating functional dyspepsia was evaluated with costeffectiveness analysis.Results: The obvious effective rate and total effective rate of Dalitong granule in the treatment of functional dyspepsia were slightly higher than mosapride.Dalitong grunule had good safety profile, and the incidence of adverse events was lower than mosapride. During the 4 weeks of treatment, Dalitong granule had better effects than mosapride, but the cost was slightly higher.Conclusion:Dalitong granule had advantage in treating functional dyspepsia compared to mosapride. The incremental cost effectiveness ratio was mainly influenced by the price.
