CAJ | 학술논문

目的：揭示甘草自然生长发育过程主要活性成分和内源激素含量的动态变化规律。方法通过测定1年生甘草4月下旬至10月下旬中主要活性成分甘草酸、甘草苷、甘草素、异甘草素和内源激素类成分赤霉素（ GA3）、脱落酸（ ABA）、茉莉酸（ JA）、吲哚乙酸（ IAA）、水杨酸（ SA）含量，分析动态变化规律。结果主要活性成分甘草酸和甘草素的含量随着生长发育不断上升，甘草苷含量呈现先升高后降低的倒V型变化趋势，而异甘草素含量则与之相反呈现先降低后升高的V型变化趋势，两者均在8月26日出现转折点；激素类成分GA3含量受植物生长发育的时间影响显著，ABA的含量基本呈现平稳的趋势，SA和JA的含量均在8月26日达到最高点。结论甘草主要活性成分随甘草的生长发育不断积累，但含量并非都保持持续增长状态，内源激素类成分含量受时间和环境影响较大，其结果的进一步解析有利于化学调控手段在科研生产上的应用，为提高甘草药材质量提供参考依据。
목적：게시감초자연생장발육과정주요활성성분화내원격소함량적동태변화규률。방법통과측정1년생감초4월하순지10월하순중주요활성성분감초산、감초감、감초소、이감초소화내원격소류성분적매소（ GA3）、탈락산（ ABA）、말리산（ JA）、신타을산（ IAA）、수양산（ SA）함량，분석동태변화규률。결과주요활성성분감초산화감초소적함량수착생장발육불단상승，감초감함량정현선승고후강저적도V형변화추세，이이감초소함량칙여지상반정현선강저후승고적V형변화추세，량자균재8월26일출현전절점；격소류성분GA3함량수식물생장발육적시간영향현저，ABA적함량기본정현평은적추세，SA화JA적함량균재8월26일체도최고점。결론감초주요활성성분수감초적생장발육불단적루，단함량병비도보지지속증장상태，내원격소류성분함량수시간화배경영향교대，기결과적진일보해석유리우화학조공수단재과연생산상적응용，위제고감초약재질량제공삼고의거。
Objective To study the dynamic variation of main active ingredients and phytohormones in Glycyrrhiza uralensis.Methods The levels of major active ingredieats ( glycyrrhizic acid, liquiritin, liquiritigenin, isoliquiritigenin ) and phytohormones, including gibberellic acid ( GA3 ) , abscisic acid ( ABA) , jasmonic acid ( JA ) , indole-3-acetic acid ( IAA ) , and salicylic acid ( SA ) in Glycyrrhiza uralensis grown from latter part of April to latter part of October were measured.The dynamic variation feature was summarized by analyzing trends of those data.Results The levels of glycyrrhizic acid and liquiritigenin increased along with plant growth.The level of liquiritin increased firstly then decreased while isoliquiritigenin decreased at first then increased afterwards.Both of them reached to a turning point on August 26th.When it came to phytohormones, the content of GA3 was significantly influenced by the plant growth, while ABA showed a trend of plateau.SA and JA both reached the peak on August 26th. Conclusion The main active ingredients were constantly accumulated with plant growth, but its content did not necessarily keep a rising trend.The content of endogenous hormonal ingredients was greatly influenced by time and environment.Further analysis of the results was helpful to implement the chemical regulation in medical research and production.It could also provide certain reference basis for improving the medical quality of Glycyrrhiza uralensis.