CAJ | 학술논문

微生态学研究发现，人体体表及体内存在着大量的共生菌群，其中大部分寄居在人体肠道中。定植于宿主肠道内的菌群与宿主、环境3者之间构成了呈动态平衡的统一体。对肠道微生态学的研究主要是探讨健康人体的肠道菌群结构和功能，以及菌群结构紊乱对人体健康的影响，并用微生态干预手段引导宿主向健康方向发展。而中医学之体质是人体生命过程中，在先天禀赋和后天获得的基础上所形成的形态结构、生理功能和心理状态方面综合的、相对稳定的固有特质。由于肠道微生物参与人体诸多方面的生命活动，菌群的变化可以反映宿主的生理病理状态，采用肠道微生态学的研究方法研究中医体质，将对个体化诊疗产生重要意义。中医体质理论的4个基本原理和3个科学问题与肠道微生态学基本理论互相存在着很多关联性和阐释性。根据现代肠道微生态的研究成果，将中医体质理论与现代肠道微生态理念结合起来，对中医体质的4个基本原理和3个关键科学问题进行微观阐释。
미생태학연구발현，인체체표급체내존재착대량적공생균군，기중대부분기거재인체장도중。정식우숙주장도내적균군여숙주、배경3자지간구성료정동태평형적통일체。대장도미생태학적연구주요시탐토건강인체적장도균군결구화공능，이급균군결구문란대인체건강적영향，병용미생태간예수단인도숙주향건강방향발전。이중의학지체질시인체생명과정중，재선천품부화후천획득적기출상소형성적형태결구、생리공능화심리상태방면종합적、상대은정적고유특질。유우장도미생물삼여인체제다방면적생명활동，균군적변화가이반영숙주적생리병리상태，채용장도미생태학적연구방법연구중의체질，장대개체화진료산생중요의의。중의체질이론적4개기본원리화3개과학문제여장도미생태학기본이론호상존재착흔다관련성화천석성。근거현대장도미생태적연구성과，장중의체질이론여현대장도미생태이념결합기래，대중의체질적4개기본원리화3개관건과학문제진행미관천석。
Modern microecology states that there are a lot of commensal bacteria on the surface and inside human body, and most of them reside in the human intestines.The microbiota, which colonize in the gut of the host, the host, and the environment, together constitute a unity of dynamic equilibrium.Intestinal microecology is mainly to explore the structure and function of gut microbiota in the bodies of healthy human beings, to discover the influence of the structural disorder of gut microbiota on human health, and to use its intervention to guide the host to live healthily.Human ’ s constitution in TCM theory is considered as an inherent characteristic, which is formed on the basis of the prenatal and postnatal development of human beings, and affects morphology, physiology and psychology.The human gut microbiota are involved in many physiological and pathological activities, and their changes could reflect the physiological and pathological state of the host, so the research method of using intestinal microecology to study TCM constitution could be of important significance in the individual treatment.The four basic principles and three scientific questions of TCM constitutional theory are strongly interrelated with the basic theory of intestinal microecology, and they could serve as mutual interpretation.Based on the study result of modern intestinal microecology, this paper attempts to combine TCM constitutional theory with intestinal microecology, and offers microscopic interpretation of the four basic principles and the three key scientific questions of TCM constitutional theory.