CAJ | 학술논문

视网膜是经典的“神经-血管耦合”组织,将神经生物活性与血流调节融为一体.Müller细胞作为贯穿整个视网膜中的重要神经胶质细胞,连接着视网膜神经元和血视网膜屏障,在糖尿病视网膜病变的发病过程中扮演重要角色.但近年来关于Müller细胞在糖尿病视网膜病变神经损伤与微循环调节障碍中的关键作用的临床及基础研究较少.故本文将这一重要科学问题再次重申以期引起科研人员的重视.
시망막시경전적“신경-혈관우합”조직,장신경생물활성여혈류조절융위일체.Müller세포작위관천정개시망막중적중요신경효질세포,련접착시망막신경원화혈시망막병장,재당뇨병시망막병변적발병과정중분연중요각색.단근년래관우Müller세포재당뇨병시망막병변신경손상여미순배조절장애중적관건작용적림상급기출연구교소.고본문장저일중요과학문제재차중신이기인기과연인원적중시.
Retina is the classic "neurovascular coupling" tissue,and coordinate the bioactivity of neurobiology and retinal blood flow.Mü ller glia cells span the entire thickness of the tissue,and ensheath all retinal neurons and microvascular of the retina.This morphological relationship is reflected by a multitude of functional interactions between neurons and blood-retinal barrier,and play fundamental roles in diabetic retinopathy.However,in recent studies,the mechanisms of Müller glia cells in retinal neurodegeneration and microcirculatory abnormalities of diabetic retinopathy are underestimating.Therefore,the present article reaffirms the interrelationship between Müller glia cells and diabetic retinopathy to draw the attentions of researchers.