中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2015年
5期
369-373
,共5页
戴加满%李世迎%阴正勤%王刚%孟晓红
戴加滿%李世迎%陰正勤%王剛%孟曉紅
대가만%리세영%음정근%왕강%맹효홍
视网膜电描记术%视通路%视锥光感受器细胞%视网膜视杆光感受器细胞%暗适应%适应,眼
視網膜電描記術%視通路%視錐光感受器細胞%視網膜視桿光感受器細胞%暗適應%適應,眼
시망막전묘기술%시통로%시추광감수기세포%시망막시간광감수기세포%암괄응%괄응,안
Electroretinography%Visual pathways%Retinal cone photoreceptor cells%Retinal rod photoreceptor cells%Dark adaptation%Adaptation,ocular
目的 探讨视锥通路和视杆通路对人视网膜电图振荡电位时频域不同成分的贡献.方法 病例对照研究.20例受试者被分为两组,每组10例,即正常组和视锥通路异常组.所有受试者均依据ISCEV标准行双眼明暗适应3.0 ERG检查.导出数据后运用Matlab 7.0提取其振荡电位成分,傅里叶变换得到幅频图,拟合其频谱图后对组内数据比较采用配对t检验,对组间数据比较采用独立样本t检验.结果 正常组视网膜电图检查结果中暗适应3.0振荡电位不同子波成分的幅值分别为(48.63±4.29)、(158.00±32.75)、(69.27±30.31)、(38.5± 15.28)μV;视锥通路异常组分别为(4.12±3.20)、(71.25±25.43)、(48.96±20.05)、(36.84±14.26)μV.相对于正常组,视锥通路异常组前两个成分(OS1和OS2)幅值明显降低(t=16.68,5.77;P＜0.01);两组明暗适应振荡电位频域均包含两个成分(主、次频成分),相对于正常组,视锥通路异常组的明暗适应振荡电位主幅值均明显降低(t=2.72,P＜0.05,Z=-2.24,P＜0.05);而对于次幅值,在明适应振荡电位中,视锥通路异常组明显低于正常组(t=4.20,P＜0.005).结论 锥杆通路对明暗振荡电位均有贡献,视锥通路主要贡献时域内较早、频域内较高成分,视杆通路主要贡献时域内较晚、频域内较低的成分.
目的 探討視錐通路和視桿通路對人視網膜電圖振盪電位時頻域不同成分的貢獻.方法 病例對照研究.20例受試者被分為兩組,每組10例,即正常組和視錐通路異常組.所有受試者均依據ISCEV標準行雙眼明暗適應3.0 ERG檢查.導齣數據後運用Matlab 7.0提取其振盪電位成分,傅裏葉變換得到幅頻圖,擬閤其頻譜圖後對組內數據比較採用配對t檢驗,對組間數據比較採用獨立樣本t檢驗.結果 正常組視網膜電圖檢查結果中暗適應3.0振盪電位不同子波成分的幅值分彆為(48.63±4.29)、(158.00±32.75)、(69.27±30.31)、(38.5± 15.28)μV;視錐通路異常組分彆為(4.12±3.20)、(71.25±25.43)、(48.96±20.05)、(36.84±14.26)μV.相對于正常組,視錐通路異常組前兩箇成分(OS1和OS2)幅值明顯降低(t=16.68,5.77;P＜0.01);兩組明暗適應振盪電位頻域均包含兩箇成分(主、次頻成分),相對于正常組,視錐通路異常組的明暗適應振盪電位主幅值均明顯降低(t=2.72,P＜0.05,Z=-2.24,P＜0.05);而對于次幅值,在明適應振盪電位中,視錐通路異常組明顯低于正常組(t=4.20,P＜0.005).結論 錐桿通路對明暗振盪電位均有貢獻,視錐通路主要貢獻時域內較早、頻域內較高成分,視桿通路主要貢獻時域內較晚、頻域內較低的成分.
목적 탐토시추통로화시간통로대인시망막전도진탕전위시빈역불동성분적공헌.방법 병례대조연구.20례수시자피분위량조,매조10례,즉정상조화시추통로이상조.소유수시자균의거ISCEV표준행쌍안명암괄응3.0 ERG검사.도출수거후운용Matlab 7.0제취기진탕전위성분,부리협변환득도폭빈도,의합기빈보도후대조내수거비교채용배대t검험,대조간수거비교채용독립양본t검험.결과 정상조시망막전도검사결과중암괄응3.0진탕전위불동자파성분적폭치분별위(48.63±4.29)、(158.00±32.75)、(69.27±30.31)、(38.5± 15.28)μV;시추통로이상조분별위(4.12±3.20)、(71.25±25.43)、(48.96±20.05)、(36.84±14.26)μV.상대우정상조,시추통로이상조전량개성분(OS1화OS2)폭치명현강저(t=16.68,5.77;P＜0.01);량조명암괄응진탕전위빈역균포함량개성분(주、차빈성분),상대우정상조,시추통로이상조적명암괄응진탕전위주폭치균명현강저(t=2.72,P＜0.05,Z=-2.24,P＜0.05);이대우차폭치,재명괄응진탕전위중,시추통로이상조명현저우정상조(t=4.20,P＜0.005).결론 추간통로대명암진탕전위균유공헌,시추통로주요공헌시역내교조、빈역내교고성분,시간통로주요공헌시역내교만、빈역내교저적성분.
Objective To investigate the contributions of human rods and cones pathway to different components of oscillatory potentials (OP) in time and frequency domain.Methods Case-control study.Twenty subjects were divided into two groups,normal groups (NG) and cones pathway abnormal groups (CAG).All eyes were investigated by dark-adapted (DA) and light-adapted (LA) 3.0 ERG recommended by ISCEV.Data were output into the computer and processed and analyzed by the software Matlab7.0.First,to extract the OP by filter,then to get the frequency-amplitude relationship by FFT,after that the relationship was fitted by equations and lastly we statistic and analyze the parameters gotten from the equations.Results Compared with normal group[(48.63±4.29),(158.00±32.75),(69.27±30.31),(38.5± 15.28) μV],the amplitudes of the first two components of dark-adapted OP in the CAG[(4.12±3.20),(71.25 ± 25.43),(48.96 ± 20.05),(36.84 ± 14.26) μV] were significant decreased(t=16.68,5.77,P＜0.01).Frequency domain of LA and DA OP in the two groups was comprised with two components (harmonic and subharmonic).Compared with normal group,harmonic components of CAG were dramatic decreased (t=2.72,P＜0.05;Z=-2.24,P＜0.05).The value of subharmonic component in CAG was lowest in DA OP compared with NG (t=4.20,P＜0.005).Conclusions Cones and rods pathway all contributed to the DA and LA OP Cones pathway mainly contributes to the earlier and faster components of OP while the rods pathway to the later and slower components.
