CAJ | 학술논문

咪唑啉受体不仅与血压调节、胰岛素分泌、神经元保护、肾脏排钠利尿、促进细胞增殖等重要生理功能相关，还参与了抑郁症、帕金森病、海洛因成瘾、亨廷顿舞蹈病、阿尔茨海默病等多种精神神经疾病的发生过程。本文就咪唑啉受体的生物学特征及其激动剂和拮抗剂的研究进展做一综述。
미서람수체불부여혈압조절、이도소분비、신경원보호、신장배납이뇨、촉진세포증식등중요생리공능상관，환삼여료억욱증、파금삼병、해락인성은、형정돈무도병、아이자해묵병등다충정신신경질병적발생과정。본문취미서람수체적생물학특정급기격동제화길항제적연구진전주일종술。
Imidazoline receptor (IR) is not only associated with important physiological functions including blood pressure regulation,insulin secretion,neuron protection,renal natriuresis and promoting cell proliferation,but also involved in the neurological and psychiatric disorders such as depression,Parkinson′s disease,heroin addiction,Hunting-ton′s disease and Alzheimer′s disease. This paper summarizes the research progress on the biological characteristics of IR and its agonists and antagonists.