中国性科学
中國性科學
중국성과학
THE CHINESE JOURNAL OF HUMAN SEXUALITY
2015年
5期
58-60
,共3页
干扰素%尖锐湿疣%咪喹莫特乳膏
榦擾素%尖銳濕疣%咪喹莫特乳膏
간우소%첨예습우%미규막특유고
Interferon%Condyloma acuminatum%Imiquimod cream
目的：观察干扰素α－2b 皮损内注射联合咪喹莫特乳膏外搽治疗尖锐湿疣的临床疗效。方法：将58例患者随机分为治疗组和对照组，对照组28例；治疗组30例。对照组患者采用5％咪喹特乳膏外用，每周3次，睡前用药，疗程8周，治疗组采用重组干扰素α－2b 皮内注射，每次100万 U，隔日1次，疗程8周，同时联合5％咪喹莫特乳膏外用，每周3次，睡前用药。观察两种方法疗效。结果：治疗组与对照组的总有效率分别为93.3％、64.3％，两组间差异有统计学意义（χ2＝7.45，P ＜0.05）；治疗组与对照组痊愈患者随访6个月后的复发率分别为7.1％、57.1％，两组间差异有统计学意义（P ＜0.05）；两组患者的不良反应差异无统计学意义（P ＞0.05）。结论：干扰素α－2b 联合5％咪喹莫特乳膏治疗 CA 疗效显著，复发率低，值得临床使用。
目的：觀察榦擾素α－2b 皮損內註射聯閤咪喹莫特乳膏外搽治療尖銳濕疣的臨床療效。方法：將58例患者隨機分為治療組和對照組，對照組28例；治療組30例。對照組患者採用5％咪喹特乳膏外用，每週3次，睡前用藥，療程8週，治療組採用重組榦擾素α－2b 皮內註射，每次100萬 U，隔日1次，療程8週，同時聯閤5％咪喹莫特乳膏外用，每週3次，睡前用藥。觀察兩種方法療效。結果：治療組與對照組的總有效率分彆為93.3％、64.3％，兩組間差異有統計學意義（χ2＝7.45，P ＜0.05）；治療組與對照組痊愈患者隨訪6箇月後的複髮率分彆為7.1％、57.1％，兩組間差異有統計學意義（P ＜0.05）；兩組患者的不良反應差異無統計學意義（P ＞0.05）。結論：榦擾素α－2b 聯閤5％咪喹莫特乳膏治療 CA 療效顯著，複髮率低，值得臨床使用。
목적：관찰간우소α－2b 피손내주사연합미규막특유고외차치료첨예습우적림상료효。방법：장58례환자수궤분위치료조화대조조，대조조28례；치료조30례。대조조환자채용5％미규특유고외용，매주3차，수전용약，료정8주，치료조채용중조간우소α－2b 피내주사，매차100만 U，격일1차，료정8주，동시연합5％미규막특유고외용，매주3차，수전용약。관찰량충방법료효。결과：치료조여대조조적총유효솔분별위93.3％、64.3％，량조간차이유통계학의의（χ2＝7.45，P ＜0.05）；치료조여대조조전유환자수방6개월후적복발솔분별위7.1％、57.1％，량조간차이유통계학의의（P ＜0.05）；량조환자적불량반응차이무통계학의의（P ＞0.05）。결론：간우소α－2b 연합5％미규막특유고치료 CA 료효현저，복발솔저，치득림상사용。
Objectives:To observe the efficacy of intralesional injection of interferon α-2b combined with imiquimod cream on condyloma acuminatum.Methods:58 patients with condyloma accuminatum were divided into two groups randomly,the treatment group (30 patients)and the control group (28 patients).Patients in treatment group were treated by intralesional injection of interferon α-2b combined with imiquimod cream,and those in con-trol group were treated with imiquimod cream.Results:After treatment,the total effective rate in the treatment group and control group were 93.3% and 64.3% respectively,with statistically significant difference (P <0.05). After 3 months’follow -up,the recurrent rate in the treatment group and control group were 7.1% and 57.1%, with statistically significant difference (P <0.05).The adverse reactions in the two groups was not statistically sig-nificant (P >0.05).Conclusion:The treatment of intralesional injection of interferon α-2b combined with imi-quimod cream on condyloma acuminatum is effective,with low recurrence rate.
