CAJ | 학술논문

目的：对比分析炎琥宁与α-干扰素治疗小儿急性上呼吸道感染的疗效及对血清超敏C反应蛋白（hs-CRP）和白细胞介素-6（IL-6）的影响。方法：将98例急性上呼吸道感染患儿随机分为观察组49例和对照组49例。观察组患儿行炎琥宁治疗，对照组患儿行α-干扰素治疗。结果：观察组患儿临床治疗的总有效率为93.88%，对照组为81.63%，2组比较，差异具有统计学意义（P<0.05）。治疗后，2组患儿的血清hs-CRP、IL-6指标值较治疗前均下降（P<0.05），但观察组患儿各指标的下降幅度均大于对照组（P<0.05）。结论：炎琥宁治疗小儿急性上呼吸道感染的疗效要优于α-干扰素，更值得临床推广应用。
목적：대비분석염호저여α-간우소치료소인급성상호흡도감염적료효급대혈청초민C반응단백（hs-CRP）화백세포개소-6（IL-6）적영향。방법：장98례급성상호흡도감염환인수궤분위관찰조49례화대조조49례。관찰조환인행염호저치료，대조조환인행α-간우소치료。결과：관찰조환인림상치료적총유효솔위93.88%，대조조위81.63%，2조비교，차이구유통계학의의（P<0.05）。치료후，2조환인적혈청hs-CRP、IL-6지표치교치료전균하강（P<0.05），단관찰조환인각지표적하강폭도균대우대조조（P<0.05）。결론：염호저치료소인급성상호흡도감염적료효요우우α-간우소，경치득림상추엄응용。
Objective:comparative analysis of yanhuning and alpha-interferon in the treatment of infantile acute upper respira-tory tract infection and serum high-sensitivity c-reactive protein (HS-CRP) and Interleukin -6 (IL-6) effect.Methods: 98 cases of children with acute upper respiratory tract infection were randomly divided into two groups in 49 cases and 49 in the control group.Study group patients treated with yanhuning, alpha-interferon therapy control group.Results: group total effective rate of clinical treatment in children with 93.88%, group 81.63%, 2 group, the difference was statistically significant (P<0.05) . After treatment, the 2 groups of serum hs-CRP, IL-6 index values lower than before treatment (P<0.05) , but the observation group declines of the index is greater than in the control group (P<0.05) .Conclusions: the treatment of infantile acute upper respiratory tract infection with yanhuning effects was superior to alpha-interferon, deserves more clinical applications.