CAJ | 학술논문

目的：分析铜绿假单胞菌的临床分布及耐药情况，为临床合理使用抗菌药物提供依据。方法：回顾性分析本院2013年临床标本分离出的64株铜绿假单胞菌的临床分布及耐药情况。结果：64株铜绿假单胞菌主要分布在痰液、伤口分泌物中，分别占54.7%、25.0%，对16种抗菌药物体外敏感试验结果显示，复方新诺明和氯霉素耐药率最高，达100%，对其他抗菌药物均呈现不同程度的耐药。结论：铜绿假单胞菌是导致医院感染的主要病原菌之一，其耐药性比较严峻，各地区、各医院用药情况不尽相同，细菌耐药谱也不尽相同，各医院应加强对其耐药性监测，以指导临床合理用药，避免或减少耐药菌株的产生具有重要意义。
목적：분석동록가단포균적림상분포급내약정황，위림상합리사용항균약물제공의거。방법：회고성분석본원2013년림상표본분리출적64주동록가단포균적림상분포급내약정황。결과：64주동록가단포균주요분포재담액、상구분비물중，분별점54.7%、25.0%，대16충항균약물체외민감시험결과현시，복방신낙명화록매소내약솔최고，체100%，대기타항균약물균정현불동정도적내약。결론：동록가단포균시도치의원감염적주요병원균지일，기내약성비교엄준，각지구、각의원용약정황불진상동，세균내약보야불진상동，각의원응가강대기내약성감측，이지도림상합리용약，피면혹감소내약균주적산생구유중요의의。
Objective:To analyze the clinical distribution and drug resistance of Pseudomonas Aeruginosa,and provide evidence for clinical rational use of antimicrobial agents.Method:The clinical distribution and antibiotic resistance of 64 strains of Pseudomonas Aeruginosa were reviewed and analyzed in our hospital in 2013.Result:64 strains of Pseudomonas Aeruginosa were mainly distributed in the sputum,wound secretions,accounted for 54.7%,25.0%,on display in the 16 kinds of antimicrobial agents in vitro sensitivity test results,Cotrimoxazole and Chloramphenicol resistance rate were the highest,up to 100%,to the other antimicrobial agents showed different degrees of resistance.Conclusion:Pseudomonas Aeruginosa is one of the leading pathogen in nosocomial infection and its drug resistance is severe,the hospital drug use situation in various regions,different,bacterial drug resistant spectrum are not the same,all hospitals should strengthen the monitoring of drug resistance,and to guide clinical rational drug use,avoid or has an important significance to reduce the emergence of resistant strains.