CAJ | 학술논문

目的：探讨高龄老人心脏舒张功能（DHF）与骨密度之间的关系。方法选取80例多普勒组织成像（DTI）技术检测心脏收缩功能正常且年龄>80岁患者，根据二尖瓣舒张早期峰值速度/二尖瓣舒张晚期峰值速度（e/a）比值，分为心功能正常组（18例），DHF1级组（25例），DHF 2级组（22例），DHF 3级组（15例）。正常对照组为本院健康体检者20例。双能X线骨密度仪（DXA）测量骨密度（包括股骨颈、股骨总髋部和腰椎1?4）。结果与正常对照组、心功能正常组比较，DHF组（DHF1级、2级、3级）患者骨密度下降（P<0.05），随着心脏舒张功能障碍程度加重而骨密度逐渐降低，e/a比值与骨密度呈正相关（r=0.75， P<0.01）。结论高龄老人心脏舒张功能障碍程度与骨密度密切相关，心脏舒张功能障碍程度可以预测骨质疏松的发生。
목적：탐토고령노인심장서장공능（DHF）여골밀도지간적관계。방법선취80례다보륵조직성상（DTI）기술검측심장수축공능정상차년령>80세환자，근거이첨판서장조기봉치속도/이첨판서장만기봉치속도（e/a）비치，분위심공능정상조（18례），DHF1급조（25례），DHF 2급조（22례），DHF 3급조（15례）。정상대조조위본원건강체검자20례。쌍능X선골밀도의（DXA）측량골밀도（포괄고골경、고골총관부화요추1?4）。결과여정상대조조、심공능정상조비교，DHF조（DHF1급、2급、3급）환자골밀도하강（P<0.05），수착심장서장공능장애정도가중이골밀도축점강저，e/a비치여골밀도정정상관（r=0.75， P<0.01）。결론고령노인심장서장공능장애정도여골밀도밀절상관，심장서장공능장애정도가이예측골질소송적발생。
Objective To study the relationship between the severity of diastolic heart failure(DHF)and bone mineral density in the elderly. Methods Totally 80 elderly patients aged over 80 years who were tested as normal for cardiac diastolic function by Doppler tissue imaging(DTI) were selected and divided into four groups by the e/a ratio,i.e.,the normal group(n=18),the DHF 1 group(0.8≤e/a<1,n=25),the DHF 2 group (0.6≤e/a<0.8,n=22),and the DHF 3 group(e/a<0.6,n=15). And the other 20 healthy people by physical examination were set as the normal control group.All subjects underwent bone mineral density(BMD)measurement(including femoral neck,total femoral hip and lumbar vertebra 1?4) by dual energy X?ray absorptiometry. Results Bone mineral density(BMD)was significantly decreased(P<0.05)in DHF groups(DHF 1,DHF 2,and DHF 3). Bone mineral density significantly decreased along with the severity of DHF. Bone mineral density was positively correlated with the e/a ratio in the elderly with DHF(r=0.75,P<0.01). Conclusion The severity of diastolic heart failure is closely related to bone mineral density in the elderly. The severity of diastolic heart failure could predict osteoporosis.