当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2015年
15期
148-149
,共2页
过敏性结膜炎%氮卓斯汀%普拉洛芬
過敏性結膜炎%氮卓斯汀%普拉洛芬
과민성결막염%담탁사정%보랍락분
Allergic conjunctivitis%Azelastine%Pranoprofen
目的:观察氮卓斯汀联合普拉洛芬治疗过敏性结膜炎的疗效。方法选取过敏性结膜炎患者67例,随机分为试验组(n=34)和对照组(n=33),试验组给予0.5 g/L氮卓斯汀滴眼液及1 g/L普拉洛芬滴眼液,对照组仅给予0.5 g/L氮卓斯汀滴眼液,于治疗后3 d和7 d分别观察2组患者症状体征的改善情况和总体疗效。结果治疗3d后,2组患者症状体征评分均较治疗前有所改善,且试验组(6.35±2.08)优于对照组(14.82±3.13)(P<0.05);7 d后,2组评分均较3 d时进一步改善,且试验组(1.36±0.97)优于对照组(5.15±1.42)(P<0.05)。试验组3 d及7 d总有效率分别为67.6%和79.4%,高于对照组39.4%和51.5%,差异有统计学意义(P<0.05)。结论联合应用氮卓斯汀和普拉洛芬滴眼液能够有效提高过敏性结膜炎的治疗效果。
目的:觀察氮卓斯汀聯閤普拉洛芬治療過敏性結膜炎的療效。方法選取過敏性結膜炎患者67例,隨機分為試驗組(n=34)和對照組(n=33),試驗組給予0.5 g/L氮卓斯汀滴眼液及1 g/L普拉洛芬滴眼液,對照組僅給予0.5 g/L氮卓斯汀滴眼液,于治療後3 d和7 d分彆觀察2組患者癥狀體徵的改善情況和總體療效。結果治療3d後,2組患者癥狀體徵評分均較治療前有所改善,且試驗組(6.35±2.08)優于對照組(14.82±3.13)(P<0.05);7 d後,2組評分均較3 d時進一步改善,且試驗組(1.36±0.97)優于對照組(5.15±1.42)(P<0.05)。試驗組3 d及7 d總有效率分彆為67.6%和79.4%,高于對照組39.4%和51.5%,差異有統計學意義(P<0.05)。結論聯閤應用氮卓斯汀和普拉洛芬滴眼液能夠有效提高過敏性結膜炎的治療效果。
목적:관찰담탁사정연합보랍락분치료과민성결막염적료효。방법선취과민성결막염환자67례,수궤분위시험조(n=34)화대조조(n=33),시험조급여0.5 g/L담탁사정적안액급1 g/L보랍락분적안액,대조조부급여0.5 g/L담탁사정적안액,우치료후3 d화7 d분별관찰2조환자증상체정적개선정황화총체료효。결과치료3d후,2조환자증상체정평분균교치료전유소개선,차시험조(6.35±2.08)우우대조조(14.82±3.13)(P<0.05);7 d후,2조평분균교3 d시진일보개선,차시험조(1.36±0.97)우우대조조(5.15±1.42)(P<0.05)。시험조3 d급7 d총유효솔분별위67.6%화79.4%,고우대조조39.4%화51.5%,차이유통계학의의(P<0.05)。결론연합응용담탁사정화보랍락분적안액능구유효제고과민성결막염적치료효과。
Objective To observe the efficacy of allergic conjunctivitis by combining Azelastine and Pranoprofen.Methods 67 allergic conjunctivitis patients were chosen and divided into the treatment group (n=34) and the control group (n=33) randomly. The treatment group was treated with 0.5g/L Azelastine and 1g/L Pranoprofen, and the control group was just used 0.5g/L Pranoprofen. After 3 and 7 days, the improvement of symptoms and signs and efficacy both of the groups were observed.Results 3 days after the treatment, the symptoms and signs of both groups has been improved, and the treatment group (6.35±2.08) was superior to the control one (14.82±3.13) (P<0.05). 7 days later, the scores of the two groups were better than the 3 days levels, and the treatment group (1.36±0.97) was better than the control one (5.15±1.42), too(P<0.05). The effective ratio of the treatment group was 67.6%and 79.4% which were superior to the control one 39.4% and 51.5% at the 3rd and 7th days. There was significant difference between the two groups withP<0.05.Conclusion It could improve the efficacy that Azelastine and Pranoprofen was combined in the treatment of allergic conjunctivitis.