当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2015年
15期
135-136
,共2页
硫酸镁%腰麻%前列腺电切术%寒战
硫痠鎂%腰痳%前列腺電切術%寒戰
류산미%요마%전렬선전절술%한전
Magnesium sulfate%Spinal anesthesia%Transurethral resection prostatectomy%Shivering
目的:观察静脉注射硫酸镁预防腰麻下行经尿道前列腺电切(TURP)患者术中寒战发生的效果。方法选择70例美国麻醉医师协会(ASA)分级Ⅰ~Ⅱ级腰麻下行TURP术的患者,随机分为2组:硫酸镁组和生理盐水组,各35例。硫酸镁组于腰麻后20 min内缓慢静脉注射25%MgSO 4注射液80mg/kg,随后静脉泵注MgSO42g/h直至手术结束;生理盐水组则在相同时间内给予相同剂量的0.9%生理盐水。结果硫酸镁组术中有5例发生寒战反应,发生率为14.3%,生理盐水组有23例发生寒战反应,发生率为65.7%,2组寒战反应发生率比较差异有统计学意义(P<0.05);硫酸镁组均出现低体温,生理盐水组有30例出现低体温,2组差异有统计学意义(P<0.05);硫酸镁组术后血镁浓度(2.47±0.67)高于生理盐水组(0.89±0.20)(P<0.05);2组患者术后6h检查膝跳反射差异无统计学意义。结论静脉注射硫酸镁可安全、有效地防治腰麻下TURP术患者术中寒战的发生。
目的:觀察靜脈註射硫痠鎂預防腰痳下行經尿道前列腺電切(TURP)患者術中寒戰髮生的效果。方法選擇70例美國痳醉醫師協會(ASA)分級Ⅰ~Ⅱ級腰痳下行TURP術的患者,隨機分為2組:硫痠鎂組和生理鹽水組,各35例。硫痠鎂組于腰痳後20 min內緩慢靜脈註射25%MgSO 4註射液80mg/kg,隨後靜脈泵註MgSO42g/h直至手術結束;生理鹽水組則在相同時間內給予相同劑量的0.9%生理鹽水。結果硫痠鎂組術中有5例髮生寒戰反應,髮生率為14.3%,生理鹽水組有23例髮生寒戰反應,髮生率為65.7%,2組寒戰反應髮生率比較差異有統計學意義(P<0.05);硫痠鎂組均齣現低體溫,生理鹽水組有30例齣現低體溫,2組差異有統計學意義(P<0.05);硫痠鎂組術後血鎂濃度(2.47±0.67)高于生理鹽水組(0.89±0.20)(P<0.05);2組患者術後6h檢查膝跳反射差異無統計學意義。結論靜脈註射硫痠鎂可安全、有效地防治腰痳下TURP術患者術中寒戰的髮生。
목적:관찰정맥주사류산미예방요마하행경뇨도전렬선전절(TURP)환자술중한전발생적효과。방법선택70례미국마취의사협회(ASA)분급Ⅰ~Ⅱ급요마하행TURP술적환자,수궤분위2조:류산미조화생리염수조,각35례。류산미조우요마후20 min내완만정맥주사25%MgSO 4주사액80mg/kg,수후정맥빙주MgSO42g/h직지수술결속;생리염수조칙재상동시간내급여상동제량적0.9%생리염수。결과류산미조술중유5례발생한전반응,발생솔위14.3%,생리염수조유23례발생한전반응,발생솔위65.7%,2조한전반응발생솔비교차이유통계학의의(P<0.05);류산미조균출현저체온,생리염수조유30례출현저체온,2조차이유통계학의의(P<0.05);류산미조술후혈미농도(2.47±0.67)고우생리염수조(0.89±0.20)(P<0.05);2조환자술후6h검사슬도반사차이무통계학의의。결론정맥주사류산미가안전、유효지방치요마하TURP술환자술중한전적발생。
Objective To investigate the preventive effect of magnesium sulfate injection against shivering during transurethral resection prostatectomy with spinal anesthesia.Methods Seventy patients (ASAⅠ-Ⅱ) who were underwent the transurethral resection prostatectomy with spinal anesthesia were randomLy divided into the magnesium sulfate group and the control group with 35 cases in each group. In magnesium sulfate group, patients received an intravenous bolus of MgSO4 80mg/kg over a twenty-minute-period, followed by a 2g/h infusion during the intraoperative period. In control group, patients received an equal of saline during the respective time.Results The concentration of plasma Mg2+ in MgSO4 group were not different from the respective indexes in control group. In magnesium sulfate group, all patients were observed hypothermia, while in control group, 30 patients were observed hypothermia (P<0.05). In magnesium sulfate group 5 patients (14.3 percent) experienced shivering, while in control group, 23 patients (65.7 %) experienced shivering (P<0.05).Conclusion Magnesium sulfate injection performances preventive effect against shivering during transurethral resection prostatectomy with spinal anesthesia.