CAJ | 학술논문

目的：探讨主动脉瓣置换术后发生 A 型主动脉夹层的危险因素。方法选取2009年5月—2013年12月在湖北医药学院附属襄阳医院行主动脉瓣置换术后发生 A 型主动脉夹层患者25例为观察组，选取同期主动脉瓣置换术后未发生 A 型主动脉夹层患者42例为对照组，观察两组临床特征的差异，应用 logistic 多因素回归分析确定其危险因素。结果观察组年龄、主动脉瓣关闭不全及主动脉壁病理改变的发生率均高于对照组(P <0．05)。年龄、主动脉瓣关闭不全和主动脉壁病理改变是主动脉瓣置换术后发生 A 型主动脉夹层的主要危险因素。结论针对主动脉瓣置换术后发生 A 型主动脉夹层的危险因素，根据患者具体情况制定适宜手术方案，以降低发生率。
목적：탐토주동맥판치환술후발생 A 형주동맥협층적위험인소。방법선취2009년5월—2013년12월재호북의약학원부속양양의원행주동맥판치환술후발생 A 형주동맥협층환자25례위관찰조，선취동기주동맥판치환술후미발생 A 형주동맥협층환자42례위대조조，관찰량조림상특정적차이，응용 logistic 다인소회귀분석학정기위험인소。결과관찰조년령、주동맥판관폐불전급주동맥벽병리개변적발생솔균고우대조조(P <0．05)。년령、주동맥판관폐불전화주동맥벽병리개변시주동맥판치환술후발생 A 형주동맥협층적주요위험인소。결론침대주동맥판치환술후발생 A 형주동맥협층적위험인소，근거환자구체정황제정괄의수술방안，이강저발생솔。
Objective To investigate the risk factors of incidence of type A aortic dissection after aortic valve re-placement. Methods A total of 25 patients with type A aortic dissection during May 2009 and December 2013 after aor-tic valve replacement were selected as observation group, and 42 patients without type A aortic dissection after aortic valve replacement at the same period were selected as control group. The differences of clinical characteristics of the two groups were observed, and logistic multiple factor of regression analysis was used to confirm the risk factors. Results The age of the patients, the incidence rates of aortic valve insufficiency and pathological change of aortic wall in observation group were significantly higher than those in control group (P < 0. 05), and the age factor, aortic valve insufficiency and pa-thology change of aortic wall were the main risk factors of type A aortic dissection following aortic valve replacement. Conclusion According to the risk factors of incidence of type A aortic dissection following aortic valve replacement, cli-nicians should take the initiative in choosing suitable operative plans so as to reduce postoperative incidence rate of type A aortic dissection.