CAJ | 학술논문

目的：分析外科Ⅰ类切口围术期预防应用抗菌药物的基本情况及存在问题。方法对1250例外科Ⅰ类切口手术患者的围术期预防应用抗菌药物情况进行调研，并对其合理性进行分析和评价。结果外科Ⅰ类切口围术期预防性应用抗菌药物适应证不合理比例为89．92％；应用抗菌药物类别的构成比由高到低分别是：头孢类、β-内酰胺酶抑制剂类、青霉素类、氟喹诺酮类、头孢复方制剂类、大环内酯类。围术期预防性应用抗菌药物：17．52％患者术前预防性用药时间不合理，79．12％患者术后预防性用药时间不合理，12．24％患者术中追加用药方式不合理，10．80％患者联合用药不合理，64．96％患者给药次数不合理。结论外科Ⅰ类切口围术期预防应用抗菌药物在药物选择、用药时机、联合用药等方面不合理、不规范的情况比较普遍，应加强对围术期抗菌药物的使用标准的执行力度，强化管理，规范其使用。
목적：분석외과Ⅰ류절구위술기예방응용항균약물적기본정황급존재문제。방법대1250예외과Ⅰ류절구수술환자적위술기예방응용항균약물정황진행조연，병대기합이성진행분석화평개。결과외과Ⅰ류절구위술기예방성응용항균약물괄응증불합리비례위89．92％；응용항균약물유별적구성비유고도저분별시：두포류、β-내선알매억제제류、청매소류、불규낙동류、두포복방제제류、대배내지류。위술기예방성응용항균약물：17．52％환자술전예방성용약시간불합리，79．12％환자술후예방성용약시간불합리，12．24％환자술중추가용약방식불합리，10．80％환자연합용약불합리，64．96％환자급약차수불합리。결론외과Ⅰ류절구위술기예방응용항균약물재약물선택、용약시궤、연합용약등방면불합리、불규범적정황비교보편，응가강대위술기항균약물적사용표준적집행력도，강화관리，규범기사용。
Objective To analyze the surgical incision Ⅰ class perioperative use of antibiotics prophylaxis of basic situation and the existing problems.Methods In surgical Ⅰ incision surgery,1 250 cases with perioperative preventive use of antibiotics in this research,and the rationality and evaluation were analyzed.Results Surgical inci-sion Ⅰ class indications perioperative prophylactic use of antibiotics was not reasonable proportion was 89.92%.The structure of the use of antibiotics category than from high to low were:cephalosporins,beta lactamase inhibitor,penicil-lin,fluoroquinolone,cephalosporins compound preparations,large ring lactone class.Perioperative prophylactic use of antibiotics,17.52% patients with preoperative prophylactic medication time was not reasonable,79.12% of patients postoperative prophylactic medication time was not reasonable,12.24% of patients in supplementary treatment for unreasonable,10.80% patients with unreasonable combination,64.96% of patients dosing frequency was not reasona-ble.Conclusion Surgical incision Ⅰ class perioperative had antibiotics prophylaxis had some disadvantages in drug selection,medication time,unreasonable combination and so on,non -standard situation was common,so it should strengthen the enforcement of perioperative antibiotic use standard,strengthen management,standardize their use.