浙江医学教育
浙江醫學教育
절강의학교육
Zhejiang Medical Education
2015年
3期
52-54
,共3页
中药穴位离子导入%轮状病毒肠炎%血清IFN-γ%TNF-α
中藥穴位離子導入%輪狀病毒腸炎%血清IFN-γ%TNF-α
중약혈위리자도입%륜상병독장염%혈청IFN-γ%TNF-α
traditional Chinese medicine acupointiontophoresis%infantile rotavirus enteritis%serum level of IFN-γ and TNF-α
目的：观察中药穴位离子导入治疗小儿轮状病毒肠炎临床疗效，以及对血清IFN －γ、TNF－α的影响。方法：80例患儿随机分为对照组38例，以补液纠正脱水，调节肠道菌群及对症处理；治疗组42例，在对照组的基础上用中药穴位离子导入治疗，每天1次，共用5天。结果：治疗后，治疗组总有效率（90．47％）高于对照组（71?05％），差异有统计学意义（ P＜0．05）；治疗组有效提升了血清IFN －γ的水平，降低了患儿血清TNF－α的水平，与对照组比较，差异有统计学意义（ P＜0．05）。结论：中药穴位离子导入治疗小儿轮状病毒疗效较好，与提升了血清IFN －γ的水平和降低血清TNF－α的水平密切相关，能有效缓解轮状病毒肠炎患儿腹泻程度，缩短病程，是辅助治疗小儿轮状病毒肠炎较好的方法。
目的：觀察中藥穴位離子導入治療小兒輪狀病毒腸炎臨床療效，以及對血清IFN －γ、TNF－α的影響。方法：80例患兒隨機分為對照組38例，以補液糾正脫水，調節腸道菌群及對癥處理；治療組42例，在對照組的基礎上用中藥穴位離子導入治療，每天1次，共用5天。結果：治療後，治療組總有效率（90．47％）高于對照組（71?05％），差異有統計學意義（ P＜0．05）；治療組有效提升瞭血清IFN －γ的水平，降低瞭患兒血清TNF－α的水平，與對照組比較，差異有統計學意義（ P＜0．05）。結論：中藥穴位離子導入治療小兒輪狀病毒療效較好，與提升瞭血清IFN －γ的水平和降低血清TNF－α的水平密切相關，能有效緩解輪狀病毒腸炎患兒腹瀉程度，縮短病程，是輔助治療小兒輪狀病毒腸炎較好的方法。
목적：관찰중약혈위리자도입치료소인륜상병독장염림상료효，이급대혈청IFN －γ、TNF－α적영향。방법：80례환인수궤분위대조조38례，이보액규정탈수，조절장도균군급대증처리；치료조42례，재대조조적기출상용중약혈위리자도입치료，매천1차，공용5천。결과：치료후，치료조총유효솔（90．47％）고우대조조（71?05％），차이유통계학의의（ P＜0．05）；치료조유효제승료혈청IFN －γ적수평，강저료환인혈청TNF－α적수평，여대조조비교，차이유통계학의의（ P＜0．05）。결론：중약혈위리자도입치료소인륜상병독료효교호，여제승료혈청IFN －γ적수평화강저혈청TNF－α적수평밀절상관，능유효완해륜상병독장염환인복사정도，축단병정，시보조치료소인륜상병독장염교호적방법。
Objective] To observe the curative effect of traditional Chinese medicine (TCM) acupointiontophoresison auxiliary treatment of infantile rotavirus enteritis ,and its influence on the serum levels of IFN-γand TNF-α.[Method]38 out of 80 cases were randomly divided into control group ,with rehydration correct dehydration ,adjusting intestinal flora and symptomatic treatment;the other 42 cases as treatment group were treated with TCM acupointiontophoresis on the basis of the treatment for control group ,1 times per day ,sharing 5 days .[Result]After treatment ,the total effective rate in the control group was 71 . 05% ,and the treatment group was 90 .47% .Compared the treatment group with the control group ,the difference was statisti-cally significant ( P<0 .05 ) .In addition ,the serum level of IFN-γ or TNF-αin the treatment group was increased or de-creased respectively .Compared with control group ,the changes in the treatment group were statistically significant ( P<0 .05 ) . [Conclusion]TCMacupointiontophoresis has good curative effect on infantile rotavirus ,which is relative to improving the serum levels of IFN-γand reducing the serum level of TNF-α.Meanwhile ,it can effectively alleviate the degree of children with rotavirus enteritis diarrhea ,shorten the duration of symptoms ,and is a preferableauxiliary treatment of infantile rotavirus enteri-tis .
