南京中医药大学学报
南京中醫藥大學學報
남경중의약대학학보
JOURNAL OF NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
2015年
3期
206-209
,共4页
石江伟%贾玉洁%刘小溪%孟媛%于涛%韩景献
石江偉%賈玉潔%劉小溪%孟媛%于濤%韓景獻
석강위%가옥길%류소계%맹원%우도%한경헌
血管性痴呆%益气调血%扶本培元%三焦针法
血管性癡呆%益氣調血%扶本培元%三焦針法
혈관성치태%익기조혈%부본배원%삼초침법
vascular dementia%tonifying qi and regulating blood circulation%strengthening root and reinforcing the vital es-sence%Sanjiao acupuncture therapy
目的:评价三焦针法结合黄地散方药治疗轻中度血管性痴呆患者的有效性,探讨优化治疗方案。方法将270例轻中度血管性痴呆患者,随机分为综合治疗组、针刺组和西药组,各组90例。综合治疗组采用三焦针法与黄地散方药联合治疗;针刺组采用三焦针法治疗;西药组采用安理申治疗,共治疗12周,采用 ADAS-cog、ADL 进行评价,并比较3组临床疗效。结果①治疗后3组患者 ADL 评分均较治疗前有显著改善,差异均有统计学意义(P <0.05);3组行为能力组间比较差异无统计学意义(P >0.05);②治疗后3组患者 ADAS-cog 评分均较治疗前有显著改善,差异均有统计学意义(P <0.05);3组治疗12周后,ADAS-cog 评分、认知功能组间比较存在差异性(P <0.05),其中综合组优于针刺组和西药组(P <0.05),针刺组与西药组不存在统计学意义(P >0.05)。结论三焦针法配合黄地散方药可改善血管性痴呆患者远期的认知功能且提升血管性痴呆患者日常生活能力,值得临床推广应用。
目的:評價三焦針法結閤黃地散方藥治療輕中度血管性癡呆患者的有效性,探討優化治療方案。方法將270例輕中度血管性癡呆患者,隨機分為綜閤治療組、針刺組和西藥組,各組90例。綜閤治療組採用三焦針法與黃地散方藥聯閤治療;針刺組採用三焦針法治療;西藥組採用安理申治療,共治療12週,採用 ADAS-cog、ADL 進行評價,併比較3組臨床療效。結果①治療後3組患者 ADL 評分均較治療前有顯著改善,差異均有統計學意義(P <0.05);3組行為能力組間比較差異無統計學意義(P >0.05);②治療後3組患者 ADAS-cog 評分均較治療前有顯著改善,差異均有統計學意義(P <0.05);3組治療12週後,ADAS-cog 評分、認知功能組間比較存在差異性(P <0.05),其中綜閤組優于針刺組和西藥組(P <0.05),針刺組與西藥組不存在統計學意義(P >0.05)。結論三焦針法配閤黃地散方藥可改善血管性癡呆患者遠期的認知功能且提升血管性癡呆患者日常生活能力,值得臨床推廣應用。
목적:평개삼초침법결합황지산방약치료경중도혈관성치태환자적유효성,탐토우화치료방안。방법장270례경중도혈관성치태환자,수궤분위종합치료조、침자조화서약조,각조90례。종합치료조채용삼초침법여황지산방약연합치료;침자조채용삼초침법치료;서약조채용안리신치료,공치료12주,채용 ADAS-cog、ADL 진행평개,병비교3조림상료효。결과①치료후3조환자 ADL 평분균교치료전유현저개선,차이균유통계학의의(P <0.05);3조행위능력조간비교차이무통계학의의(P >0.05);②치료후3조환자 ADAS-cog 평분균교치료전유현저개선,차이균유통계학의의(P <0.05);3조치료12주후,ADAS-cog 평분、인지공능조간비교존재차이성(P <0.05),기중종합조우우침자조화서약조(P <0.05),침자조여서약조불존재통계학의의(P >0.05)。결론삼초침법배합황지산방약가개선혈관성치태환자원기적인지공능차제승혈관성치태환자일상생활능력,치득림상추엄응용。
ABSTRACT:OBJECTIVE To evaluate the efficiency of integrated Sanjiao acupuncture therapy and Huangdi Powder in trea-ting mild-moderate vascular dementia,and investigate optimum therapy.METHODS 270 cases of mild-moderate vascular de-mentia were randomly assigned to comprehensive therapy group,acupuncture therapy group and western medicine therapy group on average with 90 cases in each.The treatment of integrated Sanjiao acupuncture and Huangdi Powder,Sanjiao acu-puncture and donepezil were respectively adopted in comprehensive therapy group,acupuncture group and western medicine group for 12 weeks.The paper evaluated these three groups by busing ADAS-cog and ADL,and compared the clinical therapu-tic effects of groups.RESULTS After treatment,the ADL scores of three groups enhanced obviously which showed the sta-tistical meaning(P <0.05),as well as the ADAS-cog scores of three groups.The comparison of behavior ability in three groups had no statistical meaning(P >0.05).There was statistical meaning for the comparison of ADAS-cog scores and cogni-tive ability in three groups 12 weeks after treatment(P <0.05),and comprehensive group was better than western medicine group(P <0.05).There was no statistical meaning for the comparison between acupunture group and western medicine group (P >0.05).CONCLUSION The integration of Sanjiao acupuncture and Huangdi Powder could improve the long-term cogni-tive ability and daily life ability of patients with vascular demential,thus is worth a wide application in clinic.